SPAG1 Products
(Sperm Associated Antigen 1 (SPAG1))
Categories
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein. [provided by RefSeq, Jul 2008].
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Featured SPAG1 Categories
SPAG1 Antibodies
High quality antibodies with extensive validation data.
SPAG1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPAG1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPAG1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (4)
Cat. No.
ABIN5014338
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7192612
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN651886
Quantity
400 μL
Datasheet
Datasheet
Recommended SPAG1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970388
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6211516
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1159358
Quantity
96 tests
Datasheet
Datasheet
Recommended SPAG1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321052
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3095660
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3136094
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to SPAG1
sperm associated antigen 1 (SPAG1), sperm associated antigen 1a (spag1a), sperm associated antigen 1 (CpipJ_CPIJ006297), sperm associated antigen 1 (spag1), sperm associated antigen 1 (Spag1), cb1089, hsd-3.8, HSD-3.8, MGC162178, sp75, SP75, tpis, TPIS, wu:fj78g10Protein level used designations for SPAG1
- sperm associated antigen 1
- sperm-associated antigen 1
- TPR-containing protein involved in spermatogenesis
- infertility-related sperm protein Spag-1
- tetratricopeptide repeat-containing protein
- HSD-3.8
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