anti-Sphingosine-1-Phosphate Phosphatase 1 (SGPP1) Antibodies

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. Additionally we are shipping SGPP1 Kits (22) and SGPP1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SGPP1 81537 Q9BX95
SGPP1 81535 Q9JI99
SGPP1 81536  
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Top anti-SGPP1 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SGPP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate WB Suggested Anti-SGPP1 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated WB Western Blot: SGPP1 Antibody [NBP1-91353] - Jurkat cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$488.73
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: SGPP1 Antibody [NBP2-13303] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: SGPP1 Antibody [NBP2-13303] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Pancrease: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated IHC (p), WB SGPP1 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SGPP1 antibody detected the SGPP1 protein (arrow). SGPP1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SGPP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SGPP1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 200 μL Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB SGPP1 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$658.43
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,013.83
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 11 to 14 Days
$1,013.83
Details

Top referenced anti-SGPP1 Antibodies

  1. Human Polyclonal SGPP1 Primary Antibody for WB - ABIN4894719 : Dulneva, Lee, Oliver, Di Gleria, Kessler, Davies, Becker: The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum. in Human molecular genetics 2015 (PubMed)
    Show all 2 Pubmed References

More Antibodies against SGPP1 Interaction Partners

Human Sphingosine-1-Phosphate Phosphatase 1 (SGPP1) interaction partners

  1. the sequential expression and localization of the endogenous S1P regulators SGPP-1 and SGPL-1 and highlight their contribution to the sphingolipid rheostat in inflammation.

  2. The two gastric cancer cells transfected with pEF-SGPP1 exhibited a slower rate of growth with less adhesion. Thus, our findings provided evidence that SGPP1 may serve as a prognostic biomarker for patients with advanced gastric cancers.

  3. Study has revealed miR-27a as a tumor suppressor and has identified SGPP1 and Smad2 as novel targets of miR-27a, linking to STAT3 for regulating cancer cell proliferation, apoptosis and migration in colorectal cancer.

  4. The sphingolipid phosphatase SGPP1, an antagonist of sphingosine-1-phosphate signaling, is a target of miR-95 that promotes radiation resistance.

  5. S1P is elevated in patients with IPF, correlates with the lung function and mediates EMT.

  6. doxorubicin switches protective autophagy in SPP1-depleted cells to apoptosis by calpain-mediated Atg5 cleavage.

  7. Under normal circumstances, the retinal vascular pericytes maintain pericyte-endothelial contacts and vascular barrier function through the secretion of sphingosine 1-phosphate.

  8. SPP1 by regulating intracellular S1P homeostasis, can control the UPR and ER stress-induced autophagy.

  9. sphingosine-1-phosphate phosphatase 1 plays roles in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability

  10. sphingosine-1-phosphate phosphatase 1 has a role in epidermal growth factor-induced chemotaxis

  11. SPP-1 regulates ceramide levels in the ER and thus influences the anterograde membrane transport of both ceramide and proteins from the ER to the Golgi apparatus.

  12. Sphingosine kinase 2, but not sphingosine kinase 1, acted in concert with SPP-1 to regulate recycling of sphingosine into ceramide.

Mouse (Murine) Sphingosine-1-Phosphate Phosphatase 1 (SGPP1) interaction partners

  1. Results show that Runx1 regulates glucocorticoid sensitivity in lymphoma cells and identify an established direct target gene, Sgpp1, as an integrator of sphingolipid metabolism and responses to glucocorticoids.

  2. Data indicate that sphingosine-1-phosphate phosphatases 1 (Sgpp1) deficiency in keratinocytes causes sphingosine-1-phosphate (S1P) elevation and accelerates their differentiation.

  3. regulation of sphingolipid metabolism and apoptosis by SPP1

  4. sphingosine-1-phosphate phosphatase 1 plays roles in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability

SGPP1 Antigen Profile

Protein Summary

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000

Gene names and symbols associated with SGPP1

  • sphingosine-1-phosphate phosphatase 1 (SGPP1) antibody
  • sphingosine-1-phosphate phosphatase 1 (sgpp1) antibody
  • sphingosine-1-phosphate phosphatase 1 (Sgpp1) antibody
  • AI463453 antibody
  • MGC142448 antibody
  • sgpp1 antibody
  • SPP antibody
  • Spp1 antibody
  • SPPase1 antibody
  • Spph1 antibody

Protein level used designations for SGPP1

sphingosine-1-phosphate phosphatase 1 , sphingosine-1-phosphatase , hSPP1 , hSPPase1 , sphingosine-1-phosphatase 1 , spp1 , SPPase1 , sphingosine-1-phosphate phosphohydrolase

GENE ID SPECIES
428918 Gallus gallus
467479 Pan troglodytes
490728 Canis lupus familiaris
516881 Bos taurus
549040 Xenopus (Silurana) tropicalis
100626032 Sus scrofa
81537 Homo sapiens
81535 Mus musculus
81536 Rattus norvegicus
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