SGPP1 antibody (Middle Region)

Catalog No. ABIN2783990

The Rabbit Polyclonal anti-SGPP1 antibody (ABIN2783990) specifically detects SGPP1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio) samples.

Quick Overview for SGPP1 antibody (Middle Region) (ABIN2783990)

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGPP1 Antibody

Binding Specificity: Middle Region

Purpose: SGPP1 Antibody - middle region

Sequence: THKYAPFIII GLHLALGIFS FTLDTWSTSR GDTAEILGSG AGIACGSHVT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SGPP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SGPP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49967-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGPP1

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Alternative Name: SGPP1

Background:

Background Information: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351], Le Stunff et al., 2007 [PubMed 17895250]).

Gene Name: Sphingosine-1-phosphate phosphatase 1

Alternative Symbols: SPP-1, SPPase1

Protein Name: Sphingosine-1-phosphate phosphatase 1

Molecular Weight: 49kDa

Gene ID: 81537

NCBI Accession: NP_110418

UniProt: Q9BX95