anti-Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) Antibodies

SKA3 encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. Additionally we are shipping SKA3 Proteins (7) and many more products for this protein.

Gene Name	GeneID	UniProt
SKA3	221150	Q8IX90
SKA3	361047
SKA3	219114	Q8C263

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Top anti-SKA3 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN2786220	Cow	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$289.00	Details
ABIN1104302	Dog	Goat	Un-conjugated	ELISA, IHC, IHC (p)	50 μg	Log in to see	7 to 9 Days	$484.00	Details
ABIN652928	Human	Rabbit	Un-conjugated	FACS, IHC (p), WB	400 μL	Log in to see	10 to 11 Days	$335.50	Details
ABIN469742	Dog	Rabbit	Un-conjugated	WB	50 μg	Log in to see	7 to 9 Days	$551.83	Details
ABIN570773	Human	Goat	Un-conjugated	ELISA, WB	100 μg	Log in to see	6 to 7 Days	$242.88	Details
ABIN5555227	Human	Rabbit	Un-conjugated	EIA, WB	0.1 mg	Log in to see	8 to 11 Days	$474.10	Details
ABIN605122	Human	Rabbit	Un-conjugated	ELISA, IHC, IHC (p), WB	50 μg	Log in to see	7 to 9 Days	$484.00	Details
ABIN2464305	Human	Goat	Un-conjugated	ELISA, WB	0.1 mg	Log in to see	2 to 3 Days	$446.88	Details
ABIN783205	Human	Rabbit	Un-conjugated	EIA, IHC (p), WB	50 μg	Log in to see	6 to 8 Days	$390.50	Details
ABIN631843	Human	Rabbit	Un-conjugated	WB	50 μg	Log in to see	2 to 3 Days	$473.93	Details

SKA3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes	Applications	Host	Clonality	Conjugate
Human	, , , ,	, ,	,	, , , , ,
Rat (Rattus)	,	, ,	,
Mouse (Murine)	,	, ,	,

More product categories related to SKA3 Antibody

More Antibodies against SKA3 Interaction Partners

Human Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) interaction partners

Study shows that Cdk1 phosphorylates Ska3 to promote its direct binding to the Ndc80 complex (Ndc80C), a core outer kinetochore component, also show that this phosphorylation occurs specifically during mitosis and is required for the kinetochore localization of the Ska complex.
this report provides clear evidence that overexpression of the AURKA (show AURKA Antibodies), SKA3, and DSN1 (show DSN1 Antibodies) genes strongly correlates with the progression of colorectal adenomas to colorectal cancer
Kinetochores mature through Ska1 (show SKA1 Antibodies)/ska2 (show FAM33A Antibodies)/Ska3 complex recruitment and this is required for improved load-bearing capacity and silencing of the spindle assembly checkpoint.
over-expression of GNL3 (show E2IG3 Antibodies) and SKA3 in the PC-3 (show PCSK1 Antibodies) human prostate cancer cell line decreased in vitro cell migration and invasion
The structure of the Ska core complex is a W-shaped dimer of coiled coils, formed by intertwined interactions between Ska1 (show SKA1 Antibodies), Ska2 (show FAM33A Antibodies), and Ska3.
Data suggest that Aurora B phosphorylation antagonizes the interaction between the Ska1-3 complex and the KMN network, thereby controlling Ska recruitment to KTs and stabilization of KT-MT attachments.
Ska3 functions to coordinate checkpoint signaling from the microtubule binding sites within a kinetochore by laterally linking the individual binding sites.
C13Orf3 (now termed Ska3) localizes to the spindle and kinetochore throughout mitosis and its depletion markedly delays anaphase transition.
These data identify C13orf3 (Ska3) as an important factor for metaphase to anaphase progression and highlight the potential of combined RNAi screening and protein localisation analyses.
RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment.

Mouse (Murine) Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) interaction partners

The Ska3 subunit was only localized on spindle microtubules from the Pro-MI to MII stages in mouse oocyte meiosis and knockdown by Morpholino injection into mouse oocytes resulted in spindle movement defects and enlarged polar bodies.

SKA3 Antigen Profile

Protein Summary

This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SKA3

spindle and kinetochore associated complex subunit 3 (SKA3) antibody
spindle and kinetochore associated complex subunit 3 (Ska3) antibody
spindle and kinetochore associated complex subunit 3 (ska3) antibody
spindle and kinetochore associated complex subunit 3 L homeolog (ska3.L) antibody

C12H13ORF3 antibody
C13orf3 antibody
F630043A04Rik antibody
fc23d11 antibody
rama1 antibody
RGD1307201 antibody
si:rp71-68n21.13 antibody
wu:fc23d11 antibody

Protein level used designations for SKA3

spindle and kinetochore-associated protein 3 , spindle and kinetochore associated complex subunit 3 , Spindle and kinetochore-associated protein RAMA1

GENE ID	SPECIES
221150	Homo sapiens
361047	Rattus norvegicus
452468	Pan troglodytes
509921	Bos taurus
570479	Danio rerio
609400	Canis lupus familiaris
702839	Macaca mulatta
100055242	Equus caballus
100144945	Xenopus (Silurana) tropicalis
100158292	Xenopus laevis
100344062	Oryctolagus cuniculus
100450023	Pongo abelii
100595589	Nomascus leucogenys
219114	Mus musculus
418948	Gallus gallus
100726229	Cavia porcellus

Selected quality suppliers for anti-SKA3 (SKA3) Antibodies

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