anti-Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) Antibodies

SKA3 encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SKA3 221150 Q8IX90
SKA3 361047  
SKA3 219114 Q8C263
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Top anti-SKA3 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-SKA3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated ELISA, IHC, IHC (p) Anti-SKA3 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104302 concentration 27454 ug/ml. Anti-SKA3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of C13orf3 Antibody (Center) (ABIN652928) in Hela, 293 cell line lysates (35 µg/lane). C13orf3 (arrow) was detected using the purified polyclonal antibody. C13orf3 Antibody (Center) (ABIN652928) IHC analysis in formalin fixed and paraffin embedded testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$335.50
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$242.88
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SKA3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of SKA3 in human testis tissue lysate with SKA3 antibody at (A) 0.5 and (B) 1 µg/ml. 50 μg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB SKA3 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details

More Antibodies against SKA3 Interaction Partners

Human Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) interaction partners

  1. Study shows that Cdk1 phosphorylates Ska3 to promote its direct binding to the Ndc80 complex (Ndc80C), a core outer kinetochore component, also show that this phosphorylation occurs specifically during mitosis and is required for the kinetochore localization of the Ska complex.

  2. this report provides clear evidence that overexpression of the AURKA (show AURKA Antibodies), SKA3, and DSN1 (show DSN1 Antibodies) genes strongly correlates with the progression of colorectal adenomas to colorectal cancer

  3. Kinetochores mature through Ska1 (show SKA1 Antibodies)/ska2 (show FAM33A Antibodies)/Ska3 complex recruitment and this is required for improved load-bearing capacity and silencing of the spindle assembly checkpoint.

  4. over-expression of GNL3 (show E2IG3 Antibodies) and SKA3 in the PC-3 (show PCSK1 Antibodies) human prostate cancer cell line decreased in vitro cell migration and invasion

  5. The structure of the Ska core complex is a W-shaped dimer of coiled coils, formed by intertwined interactions between Ska1 (show SKA1 Antibodies), Ska2 (show FAM33A Antibodies), and Ska3.

  6. Data suggest that Aurora B phosphorylation antagonizes the interaction between the Ska1-3 complex and the KMN network, thereby controlling Ska recruitment to KTs and stabilization of KT-MT attachments.

  7. Ska3 functions to coordinate checkpoint signaling from the microtubule binding sites within a kinetochore by laterally linking the individual binding sites.

  8. C13Orf3 (now termed Ska3) localizes to the spindle and kinetochore throughout mitosis and its depletion markedly delays anaphase transition.

  9. These data identify C13orf3 (Ska3) as an important factor for metaphase to anaphase progression and highlight the potential of combined RNAi screening and protein localisation analyses.

  10. RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment.

Mouse (Murine) Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) interaction partners

  1. The Ska3 subunit was only localized on spindle microtubules from the Pro-MI to MII stages in mouse oocyte meiosis and knockdown by Morpholino injection into mouse oocytes resulted in spindle movement defects and enlarged polar bodies.

SKA3 Antigen Profile

Protein Summary

This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SKA3

  • spindle and kinetochore associated complex subunit 3 (SKA3) antibody
  • spindle and kinetochore associated complex subunit 3 (Ska3) antibody
  • spindle and kinetochore associated complex subunit 3 (ska3) antibody
  • spindle and kinetochore associated complex subunit 3 L homeolog (ska3.L) antibody
  • C12H13ORF3 antibody
  • C13orf3 antibody
  • F630043A04Rik antibody
  • fc23d11 antibody
  • rama1 antibody
  • RGD1307201 antibody
  • si:rp71-68n21.13 antibody
  • wu:fc23d11 antibody

Protein level used designations for SKA3

spindle and kinetochore-associated protein 3 , spindle and kinetochore associated complex subunit 3 , Spindle and kinetochore-associated protein RAMA1

GENE ID SPECIES
221150 Homo sapiens
361047 Rattus norvegicus
452468 Pan troglodytes
509921 Bos taurus
570479 Danio rerio
609400 Canis lupus familiaris
702839 Macaca mulatta
100055242 Equus caballus
100144945 Xenopus (Silurana) tropicalis
100158292 Xenopus laevis
100344062 Oryctolagus cuniculus
100450023 Pongo abelii
100595589 Nomascus leucogenys
219114 Mus musculus
418948 Gallus gallus
100726229 Cavia porcellus
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