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SC5DL encodes an enzyme of cholesterol biosynthesis. Additionally we are shipping Sterol-C5-Desaturase (ERG3 delta-5-Desaturase Homolog, S. Cerevisiae)-Like Antibodies (6) and many more products for this protein.
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The relationship between C-peptide concentrations and D5D (show FADS1 Proteins) enzyme activity estimates remained significant after adjusting for body mass index, waist circumference, and TNF-alpha (show TNF Proteins).
The EGR3 may not play a major role in schizophrenia susceptibility in the Chinese Han population.
Data, including data from studies in heterozygotic transgenic/knockout mice, suggest that Sc5d plays essential role in ultraviolet radiation-induced vitamin D3 synthesis in keratinocytes/skin. Homozygotic deletion of Sc5d is lethal in utero.
Data suggest that although cholesterol synthesis is impaired in both Dhcr7 (show DHCR7 Proteins) mutant and Sc5d(-/-) embryonic brain, synthesis of nonsterol isoprenoids may be increased and thus contribute to Smith-Lemli-Opitz syndrome and lathosterolosis pathology.
There were reduced nuclear levels of the lipogenic transcription factor sterol regulatory element binding protein-1 (show SREBF1 Proteins) in MCD (show MLYCD Proteins)-fed mice, but no consistent reduction in fatty acid synthesis genes (acetyl-CoA carboxylase and fatty acid synthase (show FASN Proteins)).
This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described.
, C-5 sterol desaturase
, delta(7)-sterol 5-desaturase
, fungal ERG3, delta-5-desaturase-like
, lathosterol 5-desaturase
, lathosterol dehydrogenase
, lathosterol oxidase
, sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like