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anti-TBC1 Domain Family, Member 10C (TBC1D10C) Antibodies

The protein encoded by TBC1D10C has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Additionally we are shipping TBC1 Domain Family, Member 10C Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TBC1D10C 374403 Q8IV04
TBC1D10C 108995 Q8C9V1
TBC1D10C 361697  
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Top anti-TBC1 Domain Family, Member 10C Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TBC1D10C Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Thymus 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TBC1D10C Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, FACS, WB ABIN190840 (2µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN190840 (0.5µg/ml) staining of Jurkat (A), (0.3ug/ml) PBM (B) and negative control A431 (C) cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$537.17
Details
Bat Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg 6 to 8 Days
$478.50
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg 15 to 19 Days
$527.03
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg 15 to 19 Days
$527.03
Details

Top referenced anti-TBC1 Domain Family, Member 10C Antibodies

  1. Human Polyclonal TBC1D10C Primary Antibody for IHC (p), WB - ABIN541615 : Weil, Israël: Deciphering the pathway from the TCR to NF-kappaB. in Cell death and differentiation 2006 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TBC1D10C Primary Antibody for IHC (p), WB - ABIN541616 : Im, Rao: Activation and deactivation of gene expression by Ca2+/calcineurin-NFAT-mediated signaling. in Molecules and cells 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal TBC1D10C Primary Antibody for IHC, ELISA - ABIN1001983 : White, Pasztor, Richardson, Zon: The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4. in Cytogenetics and cell genetics 2000 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal TBC1D10C Primary Antibody for IHC, ELISA - ABIN1001984 : Pan, Sun, Kardian, Whartenby, Pardoll, Liu: Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. in Nature 2007 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal TBC1D10C Primary Antibody for IHC (p), WB - ABIN2477883 : Chalon, Stein, Stein, Ratner: Letter: Sarcomatous cells in tracheobronchial secretions obtained from a specimen aspirated during surgery. in Acta cytologica 1975 (PubMed)
    Show all 4 Pubmed References

More Antibodies against TBC1 Domain Family, Member 10C Interaction Partners

Human TBC1 Domain Family, Member 10C (TBC1D10C) interaction partners

  1. identify prolyl 4-hydroxylase 2 (P4HA2) as a specific proline hydroxylase of Carabin. Carabin hydroxylation leads to its proteasomal degradation, thereby activating the Ras/extracellular signal-regulated kinase pathway and increasing B-cell lymphoma proliferation.

  2. Carabin as a new negative regulator of B-cell function, whose deficiency in B cells speeds up early B-cell responses

  3. Carabin inhibits calcineurin and Ras and was identified by a yeast-two-hybrid screen with calcineurin

Mouse (Murine) TBC1 Domain Family, Member 10C (TBC1D10C) interaction partners

  1. Carabin functions as an endogenous inhibitor of calcineurin, Ras and CamKII kinase which resulted in protection against cardiac hypertrophy.

  2. Carabin as a new negative regulator of B-cell function, whose deficiency in B cells speeds up early B-cell responses

TBC1 Domain Family, Member 10C (TBC1D10C) Antigen Profile

Protein Summary

The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TBC1D10C

  • TBC1 domain family member 10C (TBC1D10C) antibody
  • TBC1 domain family, member 10c (Tbc1d10c) antibody
  • TBC1 domain family, member 10C (Tbc1d10c) antibody
  • 1810062O14Rik antibody
  • AI428527 antibody
  • CARABIN antibody
  • EPI64C antibody
  • RGD1311490 antibody

Protein level used designations for TBC1D10C

TBC1 domain family, member 10C , carabin-like , carabin , EBP50-PDZ interactor of 64 kD , TBC1 domain family, member 10c

GENE ID SPECIES
100354002 Oryctolagus cuniculus
100433438 Pongo abelii
100464747 Ailuropoda melanoleuca
100604257 Nomascus leucogenys
374403 Homo sapiens
610509 Canis lupus familiaris
100512518 Sus scrofa
108995 Mus musculus
520599 Bos taurus
361697 Rattus norvegicus
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