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Carabin Products

(TBC1 Domain Family, Member 10C (TBC1D10C))

Categories

The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013].

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Featured Carabin Categories

Carabin Antibodies

High quality antibodies with extensive validation data.

Carabin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Carabin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, FACS, WB
Validations
  • (4)
Cat. No. ABIN190840
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN499529
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN499531
Quantity 0.1 mg
Datasheet Datasheet

Recommended Carabin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3073999
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3125800
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322203
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our Carabin products

Pan, Sun, Kardian, Whartenby, Pardoll, Liu: "Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin." in: Nature, Vol. 445, Issue 7126, pp. 433-6, (2007) (PubMed).

Weil, Israël: "Deciphering the pathway from the TCR to NF-kappaB." in: Cell death and differentiation, Vol. 13, Issue 5, pp. 826-33, (2006) (PubMed).

Im, Rao: "Activation and deactivation of gene expression by Ca2+/calcineurin-NFAT-mediated signaling." in: Molecules and cells, Vol. 18, Issue 1, pp. 1-9, (2004) (PubMed).

White, Pasztor, Richardson, Zon: "The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4." in: Cytogenetics and cell genetics, Vol. 89, Issue 3-4, pp. 272-5, (2000) (PubMed).

Synonyms and alternative names related to Carabin

TBC1 domain family member 10C (TBC1D10C), TBC1 domain family, member 10c (Tbc1d10c), TBC1 domain family, member 10C (Tbc1d10c), 1810062O14Rik, AI428527, CARABIN, EPI64C, RGD1311490

Protein level used designations for Carabin

  • TBC1 domain family, member 10C
  • carabin-like
  • carabin
  • EBP50-PDZ interactor of 64 kD
  • TBC1 domain family, member 10c
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