anti-TBP-Like 1 (TBPL1) Antibodies

TBPL1 encodes a member of the TATA box-binding protein family. Additionally we are shipping TBPL1 Proteins (15) and TBPL1 Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TBPL1 9519 P62380
TBPL1 237336 P62340
TBPL1 689030  
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Top anti-TBPL1 Antibodies at

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184823 staining (2 ug/ml) of Jurkat lysate (RIPA buffer, 30 ug total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. 100 μg 6 to 7 Days
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-TBPL1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate Human kidney 100 μL 2 to 3 Days
Human Rabbit Un-conjugated WB Western blot analysis of TRF2 expression in MCF7 (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL 13 to 14 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE antibody diluted at 1:2000 ICC/IF Image TLP antibody detects TLP protein at cytoplasm by immunofluorescent analysis. Sample: NT2D1 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: TLP protein stained by TLP antibody , diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm. 100 μL 3 to 4 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of TRF2 (Phospho-Ser323) using UV treated NIH-3T3 whole cell lysates 100 μL 11 to 12 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of TRF2 (Phospho-Thr188) using 293 whole cell lysates 100 μL 11 to 12 Days
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
Bat Goat Un-conjugated WB 100 μg 11 to 14 Days
Human Rabbit Un-conjugated IHC, ELISA 100 μL 11 to 14 Days
Human Rabbit Un-conjugated WB Western blot analysis of extracts of Jurkat cells, using TERF2 antibody (ABIN1875056). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. 100 μL 11 to 13 Days

Top referenced anti-TBPL1 Antibodies

  1. Human Monoclonal TBPL1 Primary Antibody for ChIP, CyTOF - ABIN252470 : Stavropoulos, Bradshaw, Li, Pasic, Truong, Ikura, Ungrin, Meyn: The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis. in Human molecular genetics 2002 (PubMed)
    Show all 95 Pubmed References

  2. Chinese Hamster Polyclonal TBPL1 Primary Antibody for ChIP, ICC - ABIN189464 : Smith, de Lange: Tankyrase promotes telomere elongation in human cells. in Current biology : CB 2001 (PubMed)
    Show all 58 Pubmed References

  3. Human Polyclonal TBPL1 Primary Antibody for ChIP, ICC - ABIN252639 : Mearini, Chichiarelli, Zampieri, Masciarelli, DErme, Ferraro, Mattia: Interaction of EBV latent origin of replication with the nuclear matrix: identification of S/MAR sequences and protein components. in FEBS letters 2003 (PubMed)
    Show all 9 Pubmed References

  4. Human Monoclonal TBPL1 Primary Antibody for IF, IHC - ABIN2668524 : Martianov, Fimia, Dierich, Parvinen, Sassone-Corsi, Davidson: Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene. in Molecular cell 2001 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal TBPL1 Primary Antibody for WB - ABIN1875056 : Liu, Liu, Yang, Wang, Li, Zhang: Tumor suppressor microRNA-18a regulates tumor proliferation and invasion by targeting TBPL1 in colorectal cancer cells. in Molecular medicine reports 2015 (PubMed)

  6. Human Polyclonal TBPL1 Primary Antibody for ELISA, WB - ABIN249650 : Ohbayashi, Kishimoto, Makino, Shimada, Nakadai, Aoki, Kawata, Niwa, Tamura: Isolation of cDNA, chromosome mapping, and expression of the human TBP-like protein. in Biochemical and biophysical research communications 1999 (PubMed)

More Antibodies against TBPL1 Interaction Partners

Human TBP-Like 1 (TBPL1) interaction partners

  1. TLP Prevents p53 Degradation through Disrupting the p53-MDM2 Interaction.

  2. The interaction of TBP-like protein with TFIIA is essential to suppress proteasome-dependent turnover of TBP-like protein

  3. miR18a exhibits a protective role in colorectal cancer (CRC) via inhibiting proliferation, invasion and migration of CRC cells by directly targeting the TBPL1 gene.

  4. results suggest that activation of the p21 upstream promoter is mediated by interaction between specific regions of TLP and p53

  5. Western blotting and immunohistochemistry both indicated a higher TBPL1 protein expression level in colorectal cancer tissue. siRNA for TBPL1 transfection obviously slowed down the cell proliferation in both SW-620 and HT-29 cells.

  6. TLP mediates p53-governed transcriptional activation of the p21 upstream promoter.

  7. Data show that during interphase, endogenous or exogenously expressed TRF2 is located almost exclusively in the nucleolus

  8. TLF is a functional regulator of transcription with targets distinct from those of TBP.

  9. the knockdown of the endogenous TLP reduced etoposide-induced apoptosis through repression of TAp63 expression. Taken together, our present study identifies a TLP-TAp63 pathway that is further implicated in stress-induced apoptosis.

Mouse (Murine) TBP-Like 1 (TBPL1) interaction partners

  1. Trf2 forms a stable complex with TFIIA or the testis expressed paralogue ALF chaperoned in the cytoplasm by heat shock proteins. It is recruited to active haploid cell promoters together with Tbp, Taf7l and RNA polymerase II. A set of genes activated in haploid spermatids during the first wave of spermatogenesis is down-regulated by Trf2 inactivation.

  2. Overexpression and knockdown of TLP revealed that the levels of muscle-specific myosin heavy chain and the myogenic transcription factor myogenin are downregulated by TLP. The proximal AT-rich sequence of the myogenin promoter is responsible for TLP-mediated transcriptional repression.

  3. Transplantation of TRF2 overexpressing bone marrow cells into the hematopoietic system of mice resulted in the the development of T-cell lymphomas, but overexpression of the TRF2 transgene was not detectable anymore in the tumors.

  4. transcription factor IIA may regulate the intracellular molecular state and the function of TATA-binding protein-like protein (TLP) through its property of binding to TLP

  5. TBP-related factor 2 (TRF2) has a role in mouse spermatogenesis

  6. reconfirmed cytoplasmic localization of TRF2; genotoxins caused it to migrate to the nucleus; TRF2 may be involved in genotoxin-induced transcriptional regulation

  7. these results demonstrate that TRF2 increased expression is a potent oncogenic event that along with telomerase deficiency accelerates carcinogenesis, coincidental with a derepression of telomere recombination

  8. Data report on the nucleosomal organization of telomeres that have become deprotected through the deletion of the shelterin components TRF2 or POT1a/b, and show no evidence of changes or nucleosome eviction near the telomere terminus.

  9. Role of TRF2 mRNA in male germ cells: In transgenic animals deficient in TRF2, spermatid development fails during early spermiogenesis with increased apoptosis and failure to develop testicular spermatozoa. Infertility phenotype in homozygote males.

  10. Mice lacking the TBP-related factor 2 (TRF2) gene, which is highly expressed in the testis, have a severe defect in spermiogenesis. TRF2 expression is shown to be cell type- and stage-specific and play an essential regulatory role in development.

Arabidopsis thaliana TBP-Like 1 (TBPL1) interaction partners

  1. Arabidopsis Pol II is indispensable for endogenous siRNA-mediated transcriptional gene silencing (TGS) at intergenic low-copy-number loci, despite the presence of two other polymerases-Pol IV and Pol V-that specialize in TGS through siRNAs

TBPL1 Antigen Profile

Protein Summary

This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.

Gene names and symbols associated with anti-TBP-Like 1 (TBPL1) Antibodies

  • TATA-box binding protein like 1 (TBPL1) antibody
  • TATA-binding protein 1 (tbp1) antibody
  • TATA-box binding protein like 1 L homeolog (tbpl1.L) antibody
  • TATA box binding protein-like 1 (tbpl1) antibody
  • TATA-box binding protein like 1 (tbpl1) antibody
  • TATA box binding protein-like 1 (Tbpl1) antibody
  • TATA-box binding protein like 1 (Tbpl1) antibody
  • TBP-like 1 (tbpl1) antibody
  • TATA binding protein 1 (TBP1) antibody
  • 4732475G08 antibody
  • AW011832 antibody
  • AW491032 antibody
  • D18347 antibody
  • MGC:8389 antibody
  • MGC:9620 antibody
  • STD antibody
  • STUD antibody
  • TATA binding protein 1 antibody
  • TFIID-1 antibody
  • tlf antibody
  • tlp antibody
  • trf antibody
  • trf2 antibody
  • trp antibody
  • zgc:92340 antibody

Protein level used designations for anti-TBP-Like 1 (TBPL1) Antibodies

21-kDA TBP-like protein , TATA box-binding protein-like protein 1 , TATA box-binding protein-related factor 2 , TBP-related factor 2 , TBP-related protein , second TBP of unique DNA protein , MIID(1)-5.1 (Probe) , MIID-X630 , TATA sequence-binding protein 1 , TATA-binding factor 1 , TATA-binding protein , TATA-box binding protein , TATA-box factor 1 , TATA-box-binding protein 1 , TATA-box-binding protein 1(TATA-binding factor 1)(TATA sequence-binding protein 1) , TBI , TBP-1 , TFIID , Tbp1_PCR , hypothetical protein , miid1 , pTBI , tbp*-L13301 , transcription initiation factor TFIID TBP-1 subunit , TBP-like factor , TBP-like protein 1 , xlTLF , TATA box binding protein-like 1 , TATA box-binding protein related factor 2 , TBP-like 1 , tata box-binding protein-like protein 1 , 21 kDa TBP-like protein , TATA box binding protein-like protein

9519 Homo sapiens
542240 Zea mays
395517 Gallus gallus
399086 Xenopus laevis
463010 Pan troglodytes
613818 Bos taurus
100101453 Takifugu rubripes
100173239 Pongo abelii
100232377 Taeniopygia guttata
100346981 Oryctolagus cuniculus
100528854 Ictalurus punctatus
237336 Mus musculus
689030 Rattus norvegicus
403035 Danio rerio
476209 Canis lupus familiaris
820546 Arabidopsis thaliana
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