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TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3\; MIM 300506) (Kester et al., 1999 [PubMed 10488076]\; Fiorenza et al., 2001 [PubMed 11707329]).[supplied by OMIM, Mar 2008].. Additionally we are shipping TSC22D4 Antibodies (28) and and many more products for this protein.
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Data suggest transcription factor TSC22D4 inhibition as an insulin (show INS Proteins) sensitizing option in diabetes therapy.
tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.
Liver-specific ablation of TSC22D4 triggered hypertriglyceridemia through the induction of hepatic VLDL secretion.
In vitro TSC22D4 silencing with small interfering (si)RNAs blocks granule cell differentiation and inhibits neurite elongation in neuroblastoma (show ARHGEF16 Proteins) cells, pinpointing the relevance of this protein to granule cell differentiation.
Thg-1 pit (show IRF6 Proteins) is relevant to specification, proliferation/migration, differentiation, and mature function of granule/interneuron cells in different brain districts [Thg-1 pit (show IRF6 Proteins)]
TSC22D4 is stably upregulated by hyperosmolality in mIMCD3 cells and increased in renal papilla compared with cortex.
TSC-22 (show TSC22D1 Proteins) is a potential tumor suppressor that is upregulated by Flt3 (show FLT3 Proteins)-D835V but not Flt3 (show FLT3 Proteins)-ITD
Results suggest that THG-1pit is involved in the induction of granule neuron apoptosis.
TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3\; MIM 300506) (Kester et al., 1999
TSC22 domain family, member 4
, TSC22 domain family 4
, TSC22 domain family protein 4
, TSC22-related-inducible leucine zipper protein 2
, tsc-22-like protein THG-1
, TSC22-related inducible leucine zipper 2