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Cancer-associated chromosomal changes often involve regions containing fragile sites. Additionally we are shipping Testis Derived Transcript (3 LIM Domains) Antibodies (40) and Testis Derived Transcript (3 LIM Domains) Kits (12) and many more products for this protein.
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Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
, testis derived transcript (3 LIM domains)
, testin 2
, Testin-like protein
, testis derived transcript
, LOW QUALITY PROTEIN: testin