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May play a role in the sperm tail fibrous sheath, a major sperm tail structure.. Additionally we are shipping TSGA10 Antibodies (37) and and many more products for this protein.
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This study also shows that Tsga10 expression protects sperm dysfunction in formalin plus manganese-exposed mice resulting in better preservation of spermatozoa and improvement of male fertility.
Tsga10 plays a role in the sperm tail fibrous sheath.
Tsga10 expression starts in 4.5-7.5 dpc mouse embryos and continues throughout embryogenesis.
HIF-1alpha (show HIF1A Proteins) nuclear localization and HIF-1 (show HIF1A Proteins) transcriptional activity were significantly affected by overexpressed TSGA10
TSGA10 tends to express variants with shorter 5'UTR.
Overexpression of TSGA10 would induce disruption of HIF-1alpha (show HIF1A Proteins) axis and exert potent inhibitory effects on tumor angiogenesis and metastasis.
Report role for mir (show MLXIP Proteins)-577/TSGA10 axis in regulation esophageal squamous cell carcinoma progression.
TSGA10 should be considered as an autoantigen in a subset of autoimmune polyendocrine syndrome type 1 patients and also in a minority of systemic lupus erythematosus patients
TSGA10 could influence the function of antigen presenting cells via its interaction with cytoskeletal proteins such as vimentin (show VIM Proteins)
over-expressed in 4 of 20 hepatocellular carcinomas (HCC (show FAM126A Proteins)), 1 of 20 colon cancers, 7 of 20 ovarian cancers, 3 of 20 prostate cancers, 1 of 21 malignant melanomas, and 8 of 21 bladder cancers
The RT-PCR of TSGA10 expression may help in detection of residual clonal cells leading to early diagnosis and better prognostic qualification of the acute lymphoblastic leukemia.
TSGA10 is target of immune reactions in Autoimmune polyendocrine syndrome type 1 (APS1).
May play a role in the sperm tail fibrous sheath, a major sperm tail structure.
testis specific, 10
, testis-specific gene 10 protein
, cancer/testis antigen 79
, testis development protein NYD-SP7