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TPMT Proteins

TPMT encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct.

26 results:

Thiopurine S-Methyltransferase (TPMT) (AA 1-245) Protein Protein

TPMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Catalog No. ABIN934951
$679.46
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 1-245) protein (His tag) Protein

TPMT Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3074765
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 1-240) protein (His tag) Protein

TPMT Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3131858
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 26-227) protein (T7 tag,His tag) Protein

TPMT Origin: Human Host: Escherichia coli (E. coli) Recombinant ≥ 95 % ELISA, IP, SDS, WB
Catalog No. ABIN6236916
$420.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 4-244), (partial) protein (GST tag) Protein

TPMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5712067
$501.60
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 11 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 1-245) protein (GST tag) Protein

TPMT Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB
Catalog No. ABIN1323441
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 1-245) Protein Protein

TPMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666697
$646.15
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 15 to 19 Business Days

Thiopurine S-Methyltransferase (TPMT) protein (Myc-DYKDDDDK Tag) Protein

TPMT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2733577
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 4-244), (partial) protein (GST tag) Protein

TPMT Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA
Catalog No. ABIN1608011
$1,842.50
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days

Thiopurine S-Methyltransferase (TPMT) (AA 1-245) Protein Protein

TPMT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95.0 %
Catalog No. ABIN806388
$4,800.00
Plus shipping costs $45.00
1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days
  • Type Protein
    • Protein
  • Target Thiopurine S-Methyltransferase (TPMT)
    • Thiopurine S-Methyltransferase (TPMT)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Interleukin 8 (IL8)
    • Leptin (LEP)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • SARS-CoV-2 Spike S1
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Immunoprecipitation (IP)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reactivity
    • Human
    • Pseudomonas aeruginosa
    • African wild dog (Lycaon pictus)
    • Cat
    • Chimpanzee
    • Cow
    • Dog
    • Legionella pneumophila
    • Lion
    • Mouse
    • Pongo pygmaeus
    • Pseudomonas fluorescens
    • Rabbit
    • Rat
  • Images available
  • Host
    • Yeast
    • Escherichia coli (E. coli)
    • Insect Cells
    • HEK-293 Cells
    • Wheat germ
  • Binding Specificity
    • AA 1-245
    • AA 1-218
    • AA 1-240
    • AA 4-244
    • partial
    • AA 1-221
    • AA 26-227
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • T7 tag,His tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid

TPMT Protein Profile

Protein Summary

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Gene names and symbols associated with TPMT

  • thiopurine S-methyltransferase L homeolog (tpmt.L) antibody
  • thiopurine S-methyltransferase, tandem duplicate 2 (tpmt.2) antibody
  • thiopurine S-methyltransferase TpmT (tpmT) antibody
  • thiopurine S-methyltransferase (MCA0794) antibody
  • thiopurine S-methyltransferase (Pnap_4948) antibody
  • thiopurine S-methyltransferase (Hhal_1383) antibody
  • thiopurine S-methyltransferase (TK90_1044) antibody
  • thiopurine S-methyltransferase (Slit_1144) antibody
  • thiopurine S-methyltransferase (Tint_0842) antibody
  • Thiopurine S-methyltransferase (Fbal_3334) antibody
  • thiopurine S-methyltransferase (Celly_3188) antibody
  • thiopurine S-methyltransferase (Weevi_1737) antibody
  • Thiopurine S-methyltransferase (Psefu_2696) antibody
  • Thiopurine S-methyltransferase (Metme_3860) antibody
  • thiopurine methyltransferase (Tpmt) antibody
  • thiopurine S-methyltransferase (TPMT) antibody
  • thiopurine S-methyltransferase (Tpmt) antibody
  • AW106912 antibody
  • MGC84277 antibody
  • NHLRC1 antibody

Protein level used designations for TPMT

thiopurine S-methyltransferase , Thiopurine S-methyltransferase , S-adenosyl-L-methionine:thiopurine S-methyltransferase , thiopurine methyltransferase , NHL repeat containing 1

GENE ID SPECIES
447769 Xenopus laevis
573111 Danio rerio
1168449 Shewanella oneidensis MR-1
3104309 Methylococcus capsulatus str. Bath
4685796 Polaromonas naphthalenivorans CJ2
4711327 Halorhodospira halophila SL1
8806802 Thioalkalivibrio sp. K90mix
8891817 Sideroxydans lithotrophicus ES-1
9151573 Thiomonas intermedia K12
9772187 Ferrimonas balearica DSM 9799
10265228 Cellulophaga lytica DSM 7489
10282995 Weeksella virosa DSM 16922
10657285 Pseudomonas fulva 12-X
10673875 Methylomonas methanica MC09
22017 Mus musculus
7172 Homo sapiens
403536 Canis lupus familiaris
511644 Bos taurus
690050 Rattus norvegicus
493759 Felis catus
100034066 Equus caballus
100009411 Oryctolagus cuniculus
471863 Pan troglodytes

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