anti-Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) Antibodies

The structure of the protein encoded by TRPA1 is highly related to both the protein ankyrin and transmembrane proteins. Additionally we are shipping TRPA1 Kits (8) and TRPA1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRPA1 8989 O75762
TRPA1 277328 Q8BLA8
TRPA1 312896 Q6RI86
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Top anti-TRPA1 Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Guinea Pig Rabbit Un-conjugated ICC, IHC (fro), IF, IHC (p), IHC, WB Detection of TRPA1 in human brain membrane fraction using 2ug/ml of ABIN258315. Staining TRPA1 in mouse intestine using ABIN258315. 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Cow Rabbit Un-conjugated IF, IHC, WB <b>WB Suggested Anti-TRPA1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Stomach 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-TRPA1 antibody  ABIN1049431 IHC staining of human ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB TRPA1 antibody  ABIN1104836 (5 ug/ml) was used in IHC to stain formalin-fixed, paraffin-embedded human skeletal muscle, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 7 to 9 Days
$727.83
Details
Guinea Pig Rabbit DyLight 650 ICC, IF, IHC (fro), IHC (p), WB   0.1 mL Log in to see 7 to 9 Days
$626.75
Details
Human Rabbit Un-conjugated IHC (p) Spinal cord, DRG Immunohistochemistry-Paraffin: TRPA1 Antibody [ABIN1890820] - Analysis of anti-TRPA1 antibody with human spinal cord, dorsal root ganglion at concentration 20 ug/ml. 0.05 mg Log in to see 7 to 9 Days
$514.63
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant TRPA1, Human. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details
Gibbon Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$550.00
Details
Human Rabbit Un-conjugated WB TRPA1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details

TRPA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TRPA1 Antibodies

  1. Guinea Pig Polyclonal TRPA1 Primary Antibody for ICC, IHC (fro) - ABIN258315 : Yu, Gao, Peterson, Ouyang: TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus. in American journal of physiology. Gastrointestinal and liver physiology 2009 (PubMed)
    Show all 19 Pubmed References

  2. Cow (Bovine) Polyclonal TRPA1 Primary Antibody for IF, IHC - ABIN2776190 : Chen, Zhang, Kort, Huth, Sun, Miesbauer, Cassar, Neelands, Scott, Moreland, Reilly, Hajduk, Kym, Hutchins, Faltynek: Molecular determinants of species-specific activation or blockade of TRPA1 channels. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 (PubMed)
    Show all 5 Pubmed References

  3. Guinea Pig Polyclonal TRPA1 Primary Antibody for IHC (fro), IHC (p) - ABIN409428 : Okubo, Matsumura, Kawaishi, Aoki, Matsunami, Okawa, Sekiguchi, Kawabata: Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice. in British journal of pharmacology 2012 (PubMed)

  4. Guinea Pig Polyclonal TRPA1 Primary Antibody for ICC, IF - ABIN4362896 : Hidaka, Ogawa, Kobayashi, Suzuki, Funayama, Nagashima, Fujimura, Aiba, Nakayama, Okuyama, Yamamoto: The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. in Nature immunology 2016 (PubMed)

  5. Human Polyclonal TRPA1 Primary Antibody for IHC (p) - ABIN2476975 : Story, Gereau: Numbing the senses: role of TRPA1 in mechanical and cold sensation. in Neuron 2006 (PubMed)

More Antibodies against TRPA1 Interaction Partners

Zebrafish Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. Zebrafish TRPA1a is specialized for chemical sensing, whereas zTRPA1b responds to thermal stimuli.

  2. Inhibition of TRPA1 protein expression in zebrafish and mouse inner ears inhibits receptor cell function

  3. Larvae heterozygous for mutations in trpa1a respond to mustard oil to an extent similar to that of their wild-type siblings.

Fruit Fly (Drosophila melanogaster) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. Characterization of TRPA1 and RyR demonstrates that Ca(2 (show CA2 Antibodies)+) signaling is required for oxidative stress-induced (show SQSTM1 Antibodies) activation of the Ras/MAPK (show MAPK1 Antibodies) pathway, which in turns drives intestinal stem cell proliferation.

  2. study shows that activity/rest rhythms are modulated in a temperature-dependent manner via signals from dTRPA1(SH)-GAL4 (show LGALS4 Antibodies) driven neurons. Taken together, these results emphasize the differential influence of thermoreceptors on rhythmic behavior in fruit flies in coordination with light inputs.

  3. Rh5 (show RHO Antibodies) and Rh6 (show RHO Antibodies) were required in trpA1-expressing neurons in the brain, ventral nerve cord, and body wall. Because Rh1 (show RHO Antibodies) contributes to thermal selection in the comfortable range during the early to mid-third-instar stage, fine thermal discrimination depends on multiple rhodopsins.

  4. These findings demonstrate that Drosophila detects bacterial endotoxins via a gustatory pathway through TRPA1 activation as conserved molecular mechanism.

  5. Collectively, TRPA1 A isoform rapidly responds to natural sunlight intensities through its nucleophile sensitivity as a receptor of photochemically generated radicals, leading to an acute light-induced behavioral shift in Drosophila.

  6. H2O2-sensitive dTRPA1 isoforms promote avoidance of UV when adult Drosophila females are selecting sites for egg-laying.

  7. study concludes that the TRPA1 channel is not required for temperature synchronization but instead is required to repress activity during the warm part of the day

  8. Contribution of Drosophila TRPA1 to Metabolism.

  9. Citronellal can promote feeding deterrence of fruit flies through direct action on gustatory dTRPA1, revealing the first isoform-specific function for TRPA1(A).

  10. Recent work has uncovered the Transient Receptor Potential (TRP) channels TRPA1 mediating fly thermosensation.

Guinea Pig Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. TRPA1 activation suppresses gastric accommodation by increasing gastric tone through cholinergic neuronal pathways.

Caenorhabditis elegans (C. elegans) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. Study reveals that TRPA-1, a cold-sensitive TRP channel, detects temperature drop in the environment to extend lifespan. This effect requires cold-induced, TRPA-1-mediated calcium influx and a calcium-sensitive PKC that signals to the transcription factor DAF-16/FOXO.

  2. harsh touch specifically required the DEG/ENaC proteins MEC-10 and DEGT-1 (F25D1.4), which represent putative components of a harsh touch mechanotransduction complex; responses to cold required the TRPA-1 channel and were MEC-10 and DEGT-1 independent

  3. This study demonstrates that trpa-1 encodes an ion channel that can be activated in response to mechanical pressure and is required for mechanosensory neuron function.

Human Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. This study reveals a direct binding event and characterizes the role of TRPA1 ankyrin (show ANK Antibodies) repeats in regulating FGFR2 (show FGFR2 Antibodies)-driven oncogenic process; a mechanism that is hindered by miRNA-142-3p

  2. The results obtained with dorsal root ganglia neurons from transient receptor potential cation channel (show TRPV1 Antibodies), subfamily A (show CYP Antibodies), member 1 channels (TRPA1)-/- mice, TRPM8 (show TRPM8 Antibodies)-/- mice, and wild-type mice, using selective antagonists of TRPA1 and TRPM8 (show TRPM8 Antibodies) channels, as well as HEK293 cells stably expressing human, TRPA1, indicate that responses to cold, are mediated by TRPA1 channels.

  3. TRPA1 gene polymorphisms is associated with childhood asthma

  4. TRPM8 (show TRPM8 Antibodies), but not TRPA1, was detected in freshly isolated native human odontoblasts at the protein and mRNA levels, suggesting that odontoblasts play an important role in detecting external cold stimulation via TRPM8 (show TRPM8 Antibodies) in healthy condition.

  5. TRPV1 (show TRPV1 Antibodies) and TRPA1 also act as nociceptive sensors and potentiate the inflammatory process.

  6. neuronal effects of vinca alkaloids require the transient receptor potential ankyrin-1 (TrpA1) channel, and the hypersensitization to painful stimuli in response to the acute exposure to vinca alkaloids is reduced in TrpA1 mutant flies and mice. These findings demonstrate the direct excitation of sensory neurons by CIPN-causing chemotherapy drugs, and identify TrpA1 as an important target during the pathogenesis of CIPN

  7. The TRPA1 cation channel (show TRPV1 Antibodies) was found to be functionally expressed in primary human osteoarthritis chondrocytes, which is an original finding

  8. The findings of this study support the notion that epigenetic regulation of TRPA1 seems to regulate thermal and mechanical pain sensitivities.

  9. We provided evidence for the extraneuronal presence and upregulation of the proinflammatory TRPA1 receptor in buccal samples of patients with OLP. This may implicate the ion channel in the pathomechanism of OLP.

  10. TRPA1 DNA methylation (show HELLS Antibodies) in whole blood cells are associated with pain symptoms in chronic pain patients.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) interaction partners

  1. mmumiR449a may ameliorate neuropathic pain by decreasing the activity of the channel proteins TRPA1 and KCNMA1 (show KCNMA1 Antibodies) and increasing the levels of TPTE (show TPTE Antibodies).

  2. TRPA1, TRPV1 (show TRPV1 Antibodies) and mast cells play an indispensable role in the development of toluene-2,4-diisocyanate-elicited airway hyperreactivity

  3. The results obtained with dorsal root ganglia neurons from transient receptor potential cation channel (show TRPV1 Antibodies), subfamily A (show CYP Antibodies), member 1 channels (TRPA1)-/- mice, TRPM8 (show TRPM8 Antibodies)-/- mice, and wild-type mice, using selective antagonists of TRPA1 and TRPM8 (show TRPM8 Antibodies) channels, as well as HEK293 cells stably expressing human, TRPA1, indicate that responses to cold, are mediated by TRPA1 channels.

  4. This study demonstrated that botulinum neurotoxin A doenregulation of Trpa1 in the dorsal root ganglia in mice

  5. The TRPA1 channel may play a crucial role in neuronal development and oligodendrocyte maturation and be a potential regulator in emotion, cognition, learning and memory, and social behavior.

  6. Results identify AMPK (show PRKAA1 Antibodies) as a previously unknown regulator of TRPA1 channels. AMPK (show PRKAA1 Antibodies) modulation of TRPA1 could thus serve as an underlying mechanism and potential therapeutic molecular target in painful diabetic neuropathy.

  7. This study demonstrated that TRPA1 regulates mitogen-activated protein kinase (show MAPK1 Antibodies) pathways, as well as transcription factor c-Jun (show JUN Antibodies) and a proapoptotic Bcl-2 (show BCL2 Antibodies) family member (Bak (show BAK1 Antibodies)) expression resulting in enhanced oligodendrocyte apoptosis.

  8. Depending on the concentration, lidocaine employs TRPV1 (show TRPV1 Antibodies), TRPA1 and intracellular Ca2 (show CA2 Antibodies)+ stores to induce a Ca2 (show CA2 Antibodies)+-dependent release of the neuropeptide CGRP (show CALCA Antibodies). Lidocaine-evoked cell death does not seem to require Ca2 (show CA2 Antibodies)+ influx through TRPV1 (show TRPV1 Antibodies) or TRPV1 (show TRPV1 Antibodies)

  9. Reducing agents reverse thiazolidine-induced TRPA1 activation, and mutagenesis studies show that nucleophilic cysteine residues in TRPA1 are critical, suggesting an activation mechanism involving thioreactive chemical reactions. In vivo studies show that thiazolidine induces acute pain and inflammation in mouse and these responses are specifically dependent on TRPA1.

  10. Data show that trigeminal transient receptor potential ankyrin 1 in the nasal cavity play an essential role in irritant-induced bradypnea.

TRPA1 Antigen Profile

Protein Summary

The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined\; however, studies indicate the function may involve a role in signal transduction and growth control.

Gene names and symbols associated with TRPA1

  • transient receptor potential cation channel, subfamily A, member 1a (trpa1a) antibody
  • Transient receptor potential cation channel A1 (TrpA1) antibody
  • transient receptor potential cation channel subfamily A member 1 (TRPA1) antibody
  • transient receptor potential A1 (LOC658860) antibody
  • transient receptor potential cation channel subfamily A member 1 (LOC694623) antibody
  • tryptophan synthase subunit alpha 1 (trpA1) antibody
  • transient receptor potential cation channel, subfamily A, member 1 (trpa1) antibody
  • transient receptor potential cation channel subfamily A member 1 (Trpa1) antibody
  • TRPA cation channel homolog (trpa-1) antibody
  • transient receptor potential cation channel, subfamily A, member 1 (Trpa1) antibody
  • Anktm1 antibody
  • CG5751 antibody
  • CG5761 antibody
  • CT18073 antibody
  • dANKTM1 antibody
  • Dmel\\CG5751 antibody
  • DmTRPA1 antibody
  • dTrpA antibody
  • dtrpA1 antibody
  • FEPS antibody
  • GLEAN_02449 antibody
  • TrpA antibody
  • trpA1 antibody

Protein level used designations for TRPA1

transient receptor potential cation channel subfamily A member 1 , CG5751-PG , CG5751-PH , CG5751-PI , CG5751-PJ , CG5751-PK , TrpA1-PG , TrpA1-PH , TrpA1-PI , TrpA1-PJ , TrpA1-PK , transient receptor potential A1 , transient receptor potential cation channel , transient-receptor-potential A1 , ankyrin-like protein 1 , transient receptor potential cation channel, subfamily A, member 1 , tryptophan synthase subunit alpha 1 , transient receptor potential cation channel subfamily A member 1-like , ankyrin-like with transmembrane domains 1 , ankyrin-like with transmembrane domains protein 1 , transformation-sensitive protein p120 , ANKTM1

GENE ID SPECIES
474351 Danio rerio
39015 Drosophila melanogaster
420180 Gallus gallus
464230 Pan troglodytes
486994 Canis lupus familiaris
505317 Bos taurus
658860 Tribolium castaneum
694623 Macaca mulatta
9895859 Achromobacter xylosoxidans A8
100152934 Sus scrofa
100158526 Xenopus (Silurana) tropicalis
100414472 Callithrix jacchus
100460642 Pongo abelii
100526649 Cavia porcellus
178118 Caenorhabditis elegans
8989 Homo sapiens
277328 Mus musculus
312896 Rattus norvegicus
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