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TRPM8 Antibodies

(Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
TRPM8 antibody TRPM8 antibody TRPM8 antibody (ABIN351223)

TRPM8 Reactivity: Rat IHC, WB Host: Rabbit Polyclonal unconjugated

TRPM8 antibody  (AA 521-552) TRPM8 antibody  (AA 521-552) TRPM8 antibody (AA 521-552) (ABIN3029240)

TRPM8 Reactivity: Human IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

TRPM8 antibody  (AA 263-292) TRPM8 antibody  (AA 263-292) TRPM8 antibody (AA 263-292) (ABIN3029242)

TRPM8 Reactivity: Human IF, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

TRPM8 Antibodies by Grade

Find TRPM8 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TRPM8 Antibodies by Reactivity

Find TRPM8 Antibodies for a variety of species such as anti-Human TRPM8, anti-Rat TRPM8, anti-Mouse TRPM8. The species listed below are among those available. Click on a link to go to the corresponding products.

TRPM8 Antibodies by Application

Find TRPM8 Antibodies validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

TRPM8 Antibodies by Host

Find TRPM8 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

TRPM8 Antibodies by Binding Specificity

Find TRPM8 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TRPM8 Antibodies by Clonality

Find available monoclonal or polyclonal TRPM8 Antibodies. Click on a link to go to the corresponding products.

TRPM8 Antibodies by Clone

Find TRPM8 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

TRPM8 Antibodies by Conjugate

Find TRPM8 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TRPM8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ICC, IF, IHC, IP, LCI, Neut, WB
Validations
  • (5)
Cat. No. ABIN7043837
Quantity 25 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7172870
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3029243
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3029244
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3029241
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Bat, Dog, Guinea Pig, Hamster, Human, Monkey, Rabbit
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN960829
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (1)
  • (2)
Cat. No. ABIN360716
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application EIA, IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN955341
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7172874
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (4)
  • (1)
Cat. No. ABIN572229
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN2776255
Quantity 100 μL
Datasheet Datasheet
Reactivity Guinea Pig, Human, Monkey, Mouse, Rat
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1049436
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN2497895
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN955342
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN360715
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our TRPM8 Antibodies

Chinigò, Grolez, Audero, Bokhobza, Bernardini, Cicero, Toillon, Bailleul, Visentin, Ruffinatti, Brysbaert, Lensink, De Ruyck, Cantelmo, Fiorio Pla, Gkika: "TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells." in: Cancers, Vol. 14, Issue 9, (2022) (PubMed).

Kim, Kim, Lee, Kim, Zheng, Lim, Yun, Jeon, Choi, Hwang: "Gpr83 Tunes Nociceptor Function, Controlling Pain." in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, (2022) (PubMed).

Grolez, Gordiendko, Clarisse, Hammadi, Desruelles, Fromont, Prevarskaya, Slomianny, Gkika: "TRPM8-androgen receptor association within lipid rafts promotes prostate cancer cell migration." in: Cell death & disease, Vol. 10, Issue 9, pp. 652, (2020) (PubMed).

Xiong, Wang, Lin, Zhang, Li, Wei, Cui, Wei, Lu, Gao, Li, Zhao, Liu, Zhu: "Activation of Transient Receptor Potential Melastatin Subtype 8 Attenuates Cold-Induced Hypertension Through Ameliorating Vascular Mitochondrial Dysfunction." in: Journal of the American Heart Association, Vol. 6, Issue 8, (2018) (PubMed).

Wang, Yu, Yan, Lei, Chai, Jiang, Yuan, Xing, Du: "TRPM8 in the negative regulation of TNFα expression during cold stress." in: Scientific reports, Vol. 7, pp. 45155, (2017) (PubMed).

Genova, Grolez, Camillo, Bernardini, Bokhobza, Richard, Scianna, Lemonnier, Valdembri, Munaron, Philips, Mattot, Serini, Prevarskaya, Gkika, Pla: "TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1." in: The Journal of cell biology, Vol. 216, Issue 7, pp. 2107-2130, (2017) (PubMed).

Miller, Rao, Wang, Liu, Wang, Gavva: "Antibodies to the extracellular pore loop of TRPM8 act as antagonists of channel activation." in: PLoS ONE, Vol. 9, Issue 9, pp. e107151, (2015) (PubMed).

Yee, Li, Kazi, Yang, Berg, Yee: "Aberrantly Over-Expressed TRPM8 Channels in Pancreatic Adenocarcinoma: Correlation with Tumor Size/Stage and Requirement for Cancer Cells Invasion." in: Cells, Vol. 3, Issue 2, pp. 500-16, (2014) (PubMed).

Ma, Yu, Zhao, Luo, Chen, Ni, Jin, Ma, Wang, Zhu, Li, Zhong, Liu, Nilius, Zhu: "Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity." in: Journal of molecular cell biology, Vol. 4, Issue 2, pp. 88-96, (2012) (PubMed).

Peabody, Pohl, Diao, Vreede, Sandstrom, Wang, Zelensky, White: "Characterization of the decision network for wing expansion in Drosophila using targeted expression of the TRPM8 channel." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 11, pp. 3343-53, (2009) (PubMed).

Aliases for TRPM8 Antibodies

transient receptor potential cation channel subfamily M member 8 (TRPM8) Antibodies
transient receptor potential cation channel subfamily M member 8b L homeolog (trpm8b.L) Antibodies
transient receptor potential cation channel subfamily M member 8 (Trpm8) Antibodies
transient receptor potential cation channel, subfamily M, member 8 (Trpm8) Antibodies
transient receptor potential cation channel, subfamily M, member 8 (TRPM8) Antibodies
CMR1 Antibodies
LTrpC-6 Antibodies
ltrpc6 Antibodies
LTRPC6 Antibodies
Trp-p8 Antibodies
TRPM8 Antibodies
trpm8b Antibodies
trpp8 Antibodies
TRPP8 Antibodies
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