Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
TRPV5 is a member of the transient receptor family and the TrpV subfamily.
Showing 10 out of 81 products:
Human Polyclonal TRPV5 Primary Antibody for ICC, IF - ABIN408730
van der Eerden, Hoenderop, de Vries, Schoenmaker, Buurman, Uitterlinden, Pols, Bindels, van Leeuwen: The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption. in Proceedings of the National Academy of Sciences of the United States of America 2005
Show all 2 Pubmed References
Human Polyclonal TRPV5 Primary Antibody for ELISA, WB - ABIN263199
Kennedy, Torabi, Kurzawa, Echtenkamp, Mangini: Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium. in Molecular vision 2010
Show all 2 Pubmed References
Cow (Bovine) Polyclonal TRPV5 Primary Antibody for IHC, WB - ABIN2783755
Cha, Wu, Huang: Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5. in American journal of physiology. Renal physiology 2008
TRPV5 and TRPV6 (show TRPV6 Antibodies) lack a positively charged residue in the TM4 (show TPM4 Antibodies)-TM5 loop that was shown to interact with PI(4,5)P2 in TRPV1 (show TRPV1 Antibodies), which shows high affinity for this lipid
The alterations may lead to misfolding of TRPV5, reduction in translocation of the channel to the plasma membrane and/or impaired Ca(2 (show CA2 Antibodies)+) transport function of the channel, and ultimately disrupt TRPV5-mediated Ca(2 (show CA2 Antibodies)+) reabsorption.
These findings indicate that the A563T variation induces structural, dynamical, and electrostatic changes in the TRPV5 pore, providing structural insight into the functional alterations associated with the A563T variation.
Data found that a TRPV5 polymorphism (rs4236480) was observed to be associated with stone multiplicity of calcium nephrolithiasis, as the risk of stone multiplicity was higher in patients with the TT+CT genotype than in patients with the CC genotype
High TRPV5 expression is aassociated with adenoma of parathyroid glands.
Klotho (show KL Antibodies) up-regulates TRPV5 from both the inside and outside of cells.
Decreased expression of TRPV5 is associated with non-small cell lung cancer.
Upregulating the expression of TRPV5 can be utilized to manipulate transmembrane Ca2 (show CA2 Antibodies)+ transport, and may serve as an alternative for the treatment of Ca2 (show CA2 Antibodies)+ balance-related diseases.
These results suggest that TRPV5 and TRPV6 (show TRPV6 Antibodies) are crucial gates controlling cadmium and zinc levels in the human body.
these data showed that TRPV5/TRPV6 (show TRPV6 Antibodies) in human lymphocytes are functionally active, and their activity is associated with proliferative status of blood cells.
life-long challenge of Ca2 (show CA2 Antibodies)+ homeostasis present in Trpv5-/- mice causes accelerated bone aging and a low cortical and trabecular bone mass phenotype
beta-gal (show GLB1 Antibodies) is present in the pro-urine from where it is thought to stimulate TRPV5 activity.
A novel primary cell model with TRPV5-dependent Ca(2 (show CA2 Antibodies)+) transport characteristics was successfully established.
Phosphorylation of beta1-AR by PKA stimulates active Ca(2 (show CA2 Antibodies)+)influx through TRPV5.
The expression of TRPV5 channel is regulated by estrogen via estrogen receptor (show ESR1 Antibodies) in osteoblasts.
Uromodulin (show UMOD Antibodies) upregulates TRPV5 by decreasing caveolin-1 (show CAV1 Antibodies) dependent endocytosis of TRPV5.
In colitis in mice, tumor necrosis factor (show TNF Antibodies) and interferon-gamma (show IFNG Antibodies) reduced expression of Klotho (show KL Antibodies), which otherwise would protect TRPV5 from hypersialylation and cytokine-induced TRPV5 endocytosis, UBR4 (show UBR4 Antibodies)-dependent ubiquitination, degradation, and Ca(2 (show CA2 Antibodies)+) wasting.
The TRPV5 S682P mutant is a functionally significant factor in autosomal dominant hypercalciuria.
promoter driven Cre recombinase (show RAG1 Antibodies) expression will be useful for inducing DCT2 and CNT specific gene silencing of various channels, pumps, carriers, and receptors
Calcitonin (show CALCA Antibodies) augments the renal reabsorptive capacity for Ca(2 (show CA2 Antibodies)+). This increase is likely to occur independently of TRPV5.
mutation of a pore helix residue glutamate (show GRIN2A Antibodies)-535 to glutamine (show GFPT2 Antibodies) (E535Q) enhances the sensitivity of the channel to inhibition by extracellular protons
Results suggest that intracellular acidification directly inhibits TRPV5 by causing a conformational change(s) leading to a decrease of open probability of TRPV5 as well as of the single-channel conductance.
Activation of the CaR stimulates TRPV5-mediated Ca(2+) influx via a PMA-insensitive PKC isoform pathway.
TRPV5 and TRPV6 (show TRPV6 Antibodies) were upregulated with time and passage in culture suggesting that a shift in the phenotype of the cells in monolayer culture alters the expression of these channels.
In Equus caballus, TRPV5 mRNA is highly expressed in the kidney but scarce in the duodenum and heart. Protein expression followed a similar pattern.
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.
, calcium transporter 2
, epithelial calcium channel 1
, osm-9-like TRP channel 3
, transient receptor potential cation channel subfamily V member 5
, calcium transport protein 2
, transient receptor potential cation channel, subfamily V, member 5
, calcium transporter 2 L homeolog