Translocation Protein 1 Proteins (TLOC1)

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Additionally we are shipping Translocation Protein 1 Antibodies (34) and Translocation Protein 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TLOC1 7095 Q99442
TLOC1 69276 Q8BU14
Rat TLOC1 TLOC1 294912  
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Top Translocation Protein 1 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
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Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
Details

TLOC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Translocation Protein 1 (TLOC1) Interaction Partners

Human Translocation Protein 1 (TLOC1) interaction partners

  1. Results show higher SEC62 in the lymph node metastases from head and neck squamous cell carcinomas and cervical cancer of unknown primary patients compared with the primary tumor. Tumors from N1 to N3 stage exhibit increasing SEC62 expression in the lymphatic metastases. Its knockdown resulted in tumor cell line migration inhibition while, its overexpression stimulated cell migration.

  2. High Sec62 expression is associated with dysplastic cervical lesions.

  3. identify Sec62 as a critical molecular component in maintenance and recovery of endoplasmic reticulum homeostasis

  4. these studies identify TLOC1 and SKIL (show SKIL Proteins) as driver genes at 3q26 and more broadly suggest that cooperating genes may be coamplified in other regions with somatic copy number gain.

  5. Sec62 overproduction significantly correlates with reduced non-small lung cancer patient survival.

  6. Phosphorylation of Sec63 (show SEC63 Proteins) by CK2 (show CSNK2A1 Proteins) enhanced its binding to Sec62

  7. Silencing the SEC62 gene inhibits post-translational transport of small presecretory proteins into endoplasmic reticulum.

  8. the Sec62-dependent translocation pathway serves as a fail-safe mechanism to ensure efficient secretion of small proteins and provides cells with an opportunity to regulate secretion of small proteins independent of the signal recognition particle pathway

  9. These results revealed that cyclin B1 (show CCNB1 Proteins) and Sec62 may be candidate biomarkers and potential therapeutic targets for HBV-related HCC (show FAM126A Proteins) recurrence after surgery.

  10. The results indicate that SEC62 represents a potential candidate oncogene (show RAB1A Proteins) in the amplified 3q region in cases of non-small cell lung cancer.

Mouse (Murine) Translocation Protein 1 (TLOC1) interaction partners

  1. identify Sec62 as a critical molecular component in maintenance and recovery of endoplasmic reticulum homeostasis

  2. Interaction of ribosomes and Sec62 with the core Sec61 (show SEC61A1 Proteins) translocon is mutually exclusive.

  3. The Sec62 protein plays a role in post-translational transport of presecretory proteins into endoplasmic reticulum.

Translocation Protein 1 (TLOC1) Protein Profile

Protein Summary

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Gene names and symbols associated with TLOC1

  • SEC62 homolog, preprotein translocation factor S homeolog (sec62.S)
  • SEC62 homolog, preprotein translocation factor (SEC62)
  • SEC62 homolog, preprotein translocation factor (sec62)
  • membrane unit of ER protein translocation apparatus (SEC62)
  • SEC62 homolog (S. cerevisiae) (Sec62)
  • SEC62 homolog, preprotein translocation factor (Sec62)
  • 3100002M17Rik protein
  • Ab2-292 protein
  • AI844545 protein
  • AW545092 protein
  • Dtrp1 protein
  • HTP1 protein
  • Tloc1 protein
  • TP-1 protein
  • wu:fb57b06 protein
  • zgc:114073 protein

Protein level used designations for TLOC1

translocation protein 1 , translocation protein SEC62 , fb57b06 , uncharacterized protein LOC696989 , hypothetical protein , hTP-1 , membrane protein SEC62, S.cerevisiae, homolog of , TP-1

GENE ID SPECIES
446676 Xenopus laevis
538938 Bos taurus
563660 Danio rerio
696989 Macaca mulatta
744481 Pan troglodytes
100125961 Sus scrofa
3637124 Candida albicans SC5314
7095 Homo sapiens
69276 Mus musculus
294912 Rattus norvegicus
424993 Gallus gallus
609416 Canis lupus familiaris
100174729 Pongo abelii
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