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Transmembrane Protease, serine 15 Proteins (TMPRSS15)

TMPRSS15 encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. Additionally we are shipping Transmembrane Protease, serine 15 Antibodies (71) and Transmembrane Protease, serine 15 Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TMPRSS15 5651 P98073
TMPRSS15 19146 P97435
TMPRSS15 522055  
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Top Transmembrane Protease, serine 15 Proteins at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,493.38
Details
Escherichia coli (E. coli) Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$205.00
Details
CHO Cells Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$305.00
Details
Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 13 to 16 Days
$400.00
Details
Yeast Cow His tag 10 μg Log in to see 14 to 16 Days
$250.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
CHO Cells Human Un-conjugated   0.01 mg Log in to see 2 to 3 Days
$213.13
Details
Yeast Pig Un-conjugated   100 IU Log in to see 2 to 3 Days
$119.90
Details
CHO Cells Human Un-conjugated   50 μg Log in to see 4 to 8 Days
$328.90
Details

TMPRSS15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine)
,
Cow (Bovine) , , ,

Top referenced Transmembrane Protease, serine 15 Proteins

  1. Pig (Porcine) TMPRSS15 Protein expressed in Yeast - ABIN1574313 : Palmai-Pallag, Khodabukus, Kinarsky, Leir, Sherman, Hollingsworth, Harris: The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins. in The FEBS journal 2005 (PubMed)
    Show all 10 Pubmed References

  2. Pig (Porcine) TMPRSS15 Protein expressed in Yeast - ABIN2017741 : Hariharan, Liang, Chou, Chin: A new model for ligand release. Role of side chain in gating the enediyne antibiotic. in The Journal of biological chemistry 2006 (PubMed)
    Show all 5 Pubmed References

  3. Cow (Bovine) TMPRSS15 Protein expressed in Yeast - ABIN2001848 : Zhu, Dai, Zhang, Li, Fang, Wang, Jiang, Yu, Xia, Niu, Guo, Teng: Structural insights into the neutralization mechanism of monoclonal antibody 6C2 against ricin. in The Journal of biological chemistry 2013 (PubMed)

More Proteins for Transmembrane Protease, serine 15 (TMPRSS15) Interaction Partners

Cow (Bovine) Transmembrane Protease, serine 15 (TMPRSS15) interaction partners

  1. substrate specificities of porcine and bovine enteropeptidases were investigated using the peptide Val-(Asp)(4)-Lys-Ile-Val-Gly and its various analogs with mutations in the (Asp)(4)-Lys sequence as substrates

Human Transmembrane Protease, serine 15 (TMPRSS15) interaction partners

  1. The Y174R variant showed improved specificities for substrates containing the sequences DDDDK (kcat/KM = 6.83 x 106 M-1 sec-1) and DDDDR (kcat/KM = 1.89 x 107 M-1 sec-1) relative to all other enteropeptidase variants reported to date.

  2. Enteropeptidase is a gene associated with a starvation human phenotype and a novel target for obesity treatment

  3. Human enteropeptidase shows 10x faster kinetics compared to other animal sources but low solubility under low salt conditions. A supercharged variant of enteropeptidase light chain with increased solubility was used for crystallization.

  4. Characterization of the different catalytic activity of human and bovine enteropeptidase light chains toward hydrolysis of peptides and proteins lacking tetraaspartate sequence.

  5. Because mesotrypsin is resistant to naturally occurring trypsin inhibitors, confined expression of the isoforms of mesotrypsinogens and enteropeptidase may indicate that mesotrypsin is involved in keratinocyte terminal differentiation

  6. Engineered recombinant enteropeptidase catalytic subunit: effect of N-terminal modification

  7. Produced in enterocytes and goblet cells. Localization on brush border of cells for physiological activation of digestive enzymes. In duodenal polyps and adenocarcinoma at duodenum but not in Brunner's gland adenoma.

  8. Enterokinase directly cleaved proMMP-9 at the Lys65-Ser66 site.

Pig (Porcine) Transmembrane Protease, serine 15 (TMPRSS15) interaction partners

  1. substrate specificities of porcine and bovine enteropeptidases were investigated using the peptide Val-(Asp)(4)-Lys-Ile-Val-Gly and its various analogs with mutations in the (Asp)(4)-Lys sequence as substrates

Mouse (Murine) Transmembrane Protease, serine 15 (TMPRSS15) interaction partners

  1. Enteropeptidase could inhibit osteoclastogenesis in vitro through the cleavage of RANK.

  2. peptide sequencing of amino terminus of light chain of cow enterokinase, identifying the cleavage site

Transmembrane Protease, serine 15 (TMPRSS15) Protein Profile

Protein Summary

This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.

Gene names and symbols associated with TMPRSS15

  • Serine protease 7 (Sp7)
  • serine protease 7 (LOC733125)
  • serine protease 7 (SP7)
  • transmembrane protease, serine 7 (TMPRSS7)
  • transmembrane protease, serine 15 (TMPRSS15)
  • transmembrane protease, serine 15 (Tmprss15)
  • anon-Ryu protein
  • CG3066 protein
  • Dmel\\CG3066 protein
  • Entk protein
  • MP2 protein
  • NV14771 protein
  • PAE1 protein
  • proPO-AE protein
  • Prss7 protein
  • sp7 protein

Protein level used designations for TMPRSS15

CG3066-PA , CG3066-PB , CG3066-PC , CG3066-PD , Sp7-PA , Sp7-PB , Sp7-PC , Sp7-PD , melanization protease 2 , prophenoloxidase-activating enzyme , serine protease 7 , transmembrane protease, serine 7 , transmembrane protease serine 7 , enterokinase , enteropeptidase , protease, serine, 7 (enterokinase) , transmembrane protease serine 15 , enteropeptidase, light chain (L chain)

GENE ID SPECIES
40918 Drosophila melanogaster
733125 Bombyx mori
100114773 Nasonia vitripennis
460580 Pan troglodytes
487973 Canis lupus familiaris
522055 Bos taurus
709448 Macaca mulatta
769974 Gallus gallus
100011582 Monodelphis domestica
100061476 Equus caballus
100349681 Oryctolagus cuniculus
100392745 Callithrix jacchus
100435469 Pongo abelii
100583140 Nomascus leucogenys
282009 Bos taurus
5651 Homo sapiens
397152 Sus scrofa
19146 Mus musculus
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