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TMPRSS5 encodes a protein that belongs to the serine protease family.
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The purified IGF-binding protein-5 (IGFBP-5 (show IGFBP5 Proteins)) protease fraction secreted by cultured human osteoblasts has been characterized as ADAM9 (show ADAM9 Proteins).
Data report a newly isolated serine protease (show F2 Proteins) from mouse CNS, homologous to human spinesin type II transmembrane serine protease (show TMPRSS11E Proteins) 5 (show MASP1 Proteins) and present as a full-length protein as well as type 1, 2, and 3 variants.
Mouse spinesin is involved in function of astrocytes in spinal cord and there may be astrocyte-specific regulation of its gene expression.
This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes.
transmembrane protease, serine 5 (spinesin)
, transmembrane protease serine 5
, adrenal mitochondrial protease