Tripartite Motif Containing 33 Proteins (TRIM33)

The protein encoded by TRIM33 is thought to be a transcriptional corepressor. Additionally we are shipping TRIM33 Antibodies (118) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRIM33 51592 Q9UPN9
TRIM33 94093 Q99PP7
Rat TRIM33 TRIM33 365894  
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Top TRIM33 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,741.67
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$932.80
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$518.10
Details
Escherichia coli (E. coli) Human His tag,DYKDDDDK Tag Recombinant TRIM33 (959-1069) protein gel. TRIM33 (959-1069) protein was run on an SDS-PAGE gel and stained with Coomassie blue. 100 μg Log in to see 1 to 2 Days
$472.50
Details

TRIM33 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , , ,
Mouse (Murine)

Top referenced TRIM33 Proteins

  1. Human TRIM33 Protein expressed in HEK-293 Cells - ABIN2733719 : Labrador-Horrillo, Martínez, Selva-OCallaghan, Trallero-Araguás, Balada, Vilardell-Tarrés, Juarez: Anti-TIF1γ antibodies (anti-p155) in adult patients with dermatomyositis: comparison of different diagnostic assays. in Annals of the rheumatic diseases 2012 (PubMed)

More Proteins for Tripartite Motif Containing 33 (TRIM33) Interaction Partners

Human Tripartite Motif Containing 33 (TRIM33) interaction partners

  1. Our findings show that circPTK2 (hsa_circ_0008305) inhibits TGF-beta-induced EMT and metastasis by controlling TIF1gamma in NSCLC, revealing a novel mechanism by which circRNA regulates TGF-beta-induced EMT and tumor metastasis, and suggesting that circPTK2 overexpression could provide a therapeutic strategy for advanced NSCLC.

  2. TRIM33 acts as a cellular factor restricting HIV-1 infection by preventing provirus formation.

  3. Not only did anti-TIF1gamma antibodies correlate strongly with malignancy in dermatomyositis patients, but cancers were also significantly more advanced in anti-TIF1gamma-positive DM patients than in anti-TIF1gamma-negative patients.

  4. These results suggest that nuclear c-Abl-mediated tyrosine phosphorylation of TIF1gamma has a desuppressive role in TGF-beta-Smad2/3 signaling.

  5. Anti-TIF1gamma antibodies are rarely present in patients with solid cancers or paraneoplastic rheumatic syndromes. This finding strengthens the approach to using anti-TIF1gamma IgG as a marker for cancer-associated dermatomyositis.

  6. Tumors from paraneoplastic anti-TIF1gamma-positive cancer-associated myositis patients showed an increased number of genetic alterations, such as mutations and loss of heterozygosity, in TIF1 genes.

  7. Data show that tripartite motif-containing protein 33 (TRIM33) silencing attenuates down-regulation of MYC and TGF-beta signaling in response to bromodomain and extraterminal domain protein inhibitors (BETi).

  8. suggest that SnoN suppresses TGF-betainduced epithelial-mesenchymal transition and invasion of bladder cancer cells in a TIF1gammadependent manner

  9. The adenovirus E4-ORF3 protein functions as a SUMO E3 ligase for TIF-1gamma sumoylation and poly-SUMO chain elongation.

  10. our findings reveal a new mechanism by which SOX2-mediated transcription repression of TIF1gamma promotes TGF-beta-induced epithelial-mesenchymal transition in non-small-cell lung cancer

  11. our work indicates that TIF1gamma exerts its tumor-suppressive functions in part by promoting chromosomal stability.

  12. Results show that TRIM33 is significantly downregulated in clear renal cell carcinoma tissues which seems to correlate with pathologic stages and grades.

  13. Tumour suppressor TRIM33 targets nuclear beta-catenin degradation

  14. Study suggests TRIM33 and NRAS-CSDE1 as candidate genes for autism, and may provide a novel insight into the etiology of autism

  15. The dermatomyositis autoantigen TIF1gamma is markedly up-regulated during muscle regeneration in human and mouse muscle cells.

  16. Data indicate that tripartite motif containing 33 protein TIF1gamma promotes sumoylation of SKI-like proto-oncogene protein SnoN1 and regulates epithelial-mesenchymal transition (EMT).

  17. regulates tumor growth and metastasis through inhibition of TGF-beta/Smad signaling and may serve as a novel prognostic biomarker in hepatocellular carcinoma

  18. The ubiquitination of DHX33 by TRIM33 is lysine 63 specific and is required for the formation of the DHX33-NLRP3 inflammasome complex.

  19. Results identify a new TGFbeta regulatory layer, whereby sumoylation strengthens the TIF1gamma repressive action on canonical TGFbeta signaling.

  20. Case Report: suggest that TIF1gamma expression in neoplasms not only determines the tumour activity but also causes dermatomyositis.

Xenopus laevis Tripartite Motif Containing 33 (TRIM33) interaction partners

  1. Ectodermin is a key switch in the control of TGF-beta gene responses during early embryonic development and cell proliferation.

Mouse (Murine) Tripartite Motif Containing 33 (TRIM33) interaction partners

  1. Data show that tripartite motif 33 (TRIM33) mediates Wnt signaling by directly regulating the expression of a specific subset of Wnt target genes.

  2. Trim33 is thus revealed as being essential for the navigation of macrophages and neutrophils towards developmental or inflammatory cues within vertebrate tissues.

  3. Study reveals new important functions of TRIM33 in macrophage production and activation by LPS and pinpoints TRIM33 as an important transcriptional actor of monocyte/macrophage mediated inflammation.

  4. TRIM33 is necessary for osteoblast proliferation by regulating cell cycle and for differentiation via bone morphogenetic protein signaling pathway.

  5. these results indicate that Trim33 deficiency leads to the expansion of a subset of myeloid cells characterizing the myelodysplastic/myeloproliferative neoplasm.

  6. Trim33 altered expression of a small group of genes in the testis and the gene with the most significant increase was transcribed from an upstream RLTR10B.

  7. TRIM33 deficiency results in high expression of Ifnb1 at late stages of macrophages activation.

  8. our work indicates that TIF1gamma exerts its tumor-suppressive functions in part by promoting chromosomal stability.

  9. The findings reveal an essential role for TRIM33 in preventing apoptosis in B lymphoblastic leukemia by interfering with enhancer-mediated Bim activation.

  10. This study demonistrated that Smad4 and Trim33 regulate neural stem cells in the developing cortex in mice.

  11. Epithelium-specific Tak1:Smad4- and Trim33:Smad4-double mutants display reduced expression of Mmp13 in palatal medial edge epithelial cells.

  12. The dermatomyositis autoantigen TIF1gamma is markedly up-regulated during muscle regeneration in human and mouse muscle cells.

  13. reduces invasion and metastasis of hepatocellular carcinoma cells

  14. These data provide a new paradigm for Tif1gamma in regulating the balance between lymphoid- and myeloid-derived hematopoietic stem cells (HSC) through TGF-beta signaling, leading to HSC aging.

  15. TRIM33 plays a role in PARP-dependent DNA damage response and regulates ALC1 activity by promoting its timely removal from sites of DNA damage.

  16. TIF1gamma plays essential roles in multiple murine blood lineages and that its function in transcription elongation is evolutionally conserved.

  17. Tif1gamma suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway.

  18. Study reports an essential role for TRIM33 in the activation of Gsc and Mixl1 by nodal signals, and delineate how Smads gain access to poised promoters of master regulators under the command of nodal TGF-beta signals.

  19. Loss of Tif1g in mouse HSCs favored the expansion of the granulo-monocytic progenitor compartment & induced the age-dependent appearance of a cell-autonomous myeloproliferative disorder resembling human CMML.

  20. Somatic hepatocyte-specific inactivation of TRIM24, TRIM28, or TRIM33 all promote hepatocellular carcinoma in a cell-autonomous manner in mice.

Zebrafish Tripartite Motif Containing 33 (TRIM33) interaction partners

  1. The authors show that tif1gamma modulates the erythroid versus myeloid fate outcomes from HSCs by differentially controlling the levels of gata1 and pu.1.

  2. TIF1gamma couples the blood-specific transcriptional complex with Pol II elongation machinery to promote the transcription elongation of erythroid genes by counteracting Pol II pausing.

  3. transcriptional intermediary factor has a major role in the differentiation of hematopoietic cells

TRIM33 Protein Profile

Protein Summary

The protein encoded by this gene is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined.

Gene names and symbols associated with TRIM33

  • tripartite motif containing 33 (TRIM33)
  • tripartite motif containing 33 (trim33)
  • tripartite motif containing 33 L homeolog (trim33.L)
  • tripartite motif-containing 33 (Trim33)
  • 8030451N04Rik protein
  • AI413936 protein
  • cb1085 protein
  • Ecto protein
  • ectodermin protein
  • id:ibd2175 protein
  • MGC146665 protein
  • mKIAA1113 protein
  • mon protein
  • PTC7 protein
  • RFG7 protein
  • TF1G protein
  • Tif1g protein
  • TIF1GAMMA protein
  • TIFGAMMA protein
  • TRIM33 protein
  • wu:fc17f10 protein
  • zgc:136680 protein

Protein level used designations for TRIM33

tripartite motif-containing 33 , tripartite motif-containing 33 protein , E3 ubiquitin-protein ligase TRIM33 , e3 ubiquitin-protein ligase TRIM33-like , tripartite motif containing 33 , RET-fused gene 7 protein , TIF1-gamma , ectodermin homolog , protein Rfg7 , transcriptional intermediary factor 1 gamma , ectodermin , transcription intermediary factor 1-gamma , tripartite motif-containing protein 33 , tripartite motif protein 33 , Tif1gamma , moonshine , vampire

GENE ID SPECIES
475804 Canis lupus familiaris
100516192 Sus scrofa
419883 Gallus gallus
457141 Pan troglodytes
533296 Bos taurus
710600 Macaca mulatta
733764 Xenopus (Silurana) tropicalis
100074830 Ornithorhynchus anatinus
100231705 Taeniopygia guttata
100446018 Pongo abelii
100552000 Anolis carolinensis
100589063 Nomascus leucogenys
51592 Homo sapiens
733198 Xenopus laevis
94093 Mus musculus
365894 Rattus norvegicus
324053 Danio rerio
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