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E3 ubiquitin-protein ligase (By similarity).. Additionally we are shipping TRIM50 Antibodies (43) and many more products for this protein.
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TRIM50, via the RING domain, ubiquitinates Beclin 1 in a K63-dependent manner enhancing its binding with ULK1 and autophagy activity.
TRIM50 K372 residue competes for post-translational protein modifications such as acetylation and ubiquitination.
When the proteasome activity is impaired, TRIM50 fails to drive its substrates to the proteasome-mediated degradation.
Encodes an E3 ubiquitin ligase; putatively involved in phenotype determination of Williams-Beuren syndrome.
TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells
E3 ubiquitin-protein ligase (By similarity).
tripartite motif containing 50
, tripartite motif protein 50A
, tripartite motif-containing 50
, E3 ubiquitin-protein ligase TRIM50
, tripartite motif-containing 50A
, tripartite motif-containing protein 50
, tripartite motif protein 50