anti-Triple Functional Domain Protein (TRIO) Antibodies

Promotes the exchange of GDP by GTP. Additionally we are shipping and TRIO Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRIO 7204 O75962
TRIO 310192  
TRIO 223435 Q0KL02
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Top anti-TRIO Antibodies at

Showing 9 out of 9 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of TRIO expression in rat cardiac muscle extract (lane 1), rat skeletal muscle extract (lane 2), mouse cardiac muscle extract (lane 3), mouse skeletal muscle extract (lane 4) and HELA whole cell lysates (lane 5). TRIO at 347KD was detected using rabbit anti- TRIO Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Log in to see 4 to 6 Days
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: TRIO Sample Type: 721_B Whole Cell lysates Antibody Dilution: 1.0ug/ml  TRIO is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated ELISA, WB TRIO polyclonal antibody (A01), Lot # ABNOVA060705QCS1 Western Blot analysis of TRIO expression in HeLa . Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 11 to 12 Days
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: TRIO Antibody  - Western blot analysis in human cell line RT-4 and human cell line U-251 MG. Immunocytochemistry/Immunofluorescence: TRIO Antibody  - Staining of human cell line SH-SY5Y shows localization to cytosol. 100 μL Log in to see 10 to 13 Days
Bat Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
Zebrafish Rabbit Un-conjugated WB   400 μL Log in to see 7 to 9 Days
Cow Rabbit Un-conjugated IP, WB   100 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, IHC (p)   0.1 mL Log in to see 10 to 13 Days
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 7 to 9 Days

TRIO Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,

Rat (Rattus)

Mouse (Murine)

Top referenced anti-TRIO Antibodies

  1. Human Polyclonal TRIO Primary Antibody for ELISA, WB - ABIN563257 : Yano, Yamazaki, Adachi, Okawa, Fort, Uji, Tsukita, Tsukita: Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling. in The Journal of cell biology 2011 (PubMed)
    Show all 3 Pubmed References

More Antibodies against TRIO Interaction Partners

Human Triple Functional Domain Protein (TRIO) interaction partners

  1. A recurrent rearrangement involving TRIO with various partners was identified in 5.1% of non-translocation-related sarcoma cases. TRIO translocations are either intrachromosomal with TERT (show TERT Antibodies) or interchromosomal with LINC01504 or ZNF558 (show ZNF558 Antibodies). All translocations led to a truncated TRIO protein either directly or indirectly by alternative splicing. TRIO rearrangement is associated with a modified transcriptomic program.

  2. Study identifies a large cluster of de novo mutations in the GEF1 (show ARHGEF1 Antibodies) domain of Trio in whole-exome sequencing data from individuals with autism spectrum disorder.

  3. The findings provide a mechanism for the presynaptic targeting of Trio and support a model in which Piccolo (show PCLO Antibodies) and Bassoon (show BSN Antibodies) play a role in regulating neurotransmission through interactions with proteins, including Trio, that modulate the dynamic assembly of F-actin during cycles of synaptic vesicle exo (show PHM Antibodies)- and endocytosis.

  4. TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.

  5. our data show the importance of spatio-temporal regulation of the actin cytoskeleton through Trio and Rac1 at VE-cadherin (show CDH5 Antibodies)-based cell-cell junctions in the maintenance of the endothelial barrier.

  6. Aberrant expression of TRIO might play an important role in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) through promoting cell proliferation and invasion, and TRIO may be a novel therapeutic target for the treatment of HCC (show FAM126A Antibodies)

  7. Strong statistical evidence for a causal role of TRIO in neurodevelopmental and neuropsychiatric disorders.

  8. TRIO controls Rac1 activation in dividing cells which counteracts MgcRacGAP (show RACGAP1 Antibodies) function in cytokinesis.

  9. TRIO is an EB1 dependent MT plus end tracking protein, and forms a complex with NAV1 at growing MT ends, which regulates TRIO-mediated Rac1 activation and neurite outgrowth.

  10. Describe here an invadopodia disassembly model, where a signalling axis involving TrioGEF, Rac1, Pak1 (show PAK1 Antibodies), and phosphorylation of cortactin (show CTTN Antibodies), causes invadopodia dissolution.

Mouse (Murine) Triple Functional Domain Protein (TRIO) interaction partners

  1. The Trio gene regulates the neuronal development of the hippocampus and that it affects the intelligence of adult mice.

  2. Trio may serve as a a signal integrator decoding extrinsic signals to Rho GTPases for cytoskeleton organization

  3. M-cadherin-dependent adhesion can activate Rac1 via the Rho-GEF (show ARHGEF2 Antibodies) Trio at the time of myoblast fusion.

  4. the results show a link between Trio activity,Rac1 activation,neuronal organization,and recruitment of Cadherin-11 receptor to form a complex with Trio in hindbrain embryology.

  5. findings establish Trio as a guanine nucleotide exchange factor that mediates netrin-1 signaling in axon outgrowth and guidance through its ability to activate Rac1

TRIO Antigen Profile

Protein Summary

Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth.

Gene names and symbols associated with TRIO

  • trio Rho guanine nucleotide exchange factor (TRIO) antibody
  • trio Rho guanine nucleotide exchange factor (Trio) antibody
  • triple functional domain (PTPRF interacting) (Trio) antibody
  • trio Rho guanine nucleotide exchange factor b (triob) antibody
  • 6720464I07Rik antibody
  • AA408740 antibody
  • ARHGEF23 antibody
  • si:dz230d15.1 antibody
  • Solo antibody
  • tgat antibody

Protein level used designations for TRIO

PTPRF-interacting protein , triple functional domain (PTPRF interacting) , triple functional domain protein

7204 Homo sapiens
310192 Rattus norvegicus
223435 Mus musculus
368847 Danio rerio
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