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TRIO antibody (Internal Region)

TRIO Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257891
  • Target See all TRIO Antibodies
    TRIO (Triple Functional Domain Protein (TRIO))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 13
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIO antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Specificity
    TRIO Antibody detects endogenous levels of total TRIO.
    Predicted Reactivity
    Pig,Zebrafish,Horse,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TRIO, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    TRIO (Triple Functional Domain Protein (TRIO))
    Alternative Name
    TRIO (TRIO Products)
    Synonyms
    ARHGEF23 antibody, tgat antibody, 6720464I07Rik antibody, AA408740 antibody, Solo antibody, si:dz230d15.1 antibody, trio Rho guanine nucleotide exchange factor antibody, triple functional domain (PTPRF interacting) antibody, trio Rho guanine nucleotide exchange factor b antibody, TRIO antibody, Trio antibody, triob antibody
    Background

    Description: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).

    Gene: TRIO

    Molecular Weight
    31 kDa
    Gene ID
    7204
    UniProt
    O75962
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