TRIO antibody (AA 1961-2070)

Catalog No. ABIN563257

This Mouse Polyclonal antibody specifically detects TRIO in WB and ELISA. It exhibits reactivity toward Human. It has been mentioned in 3+ publications

Quick Overview for TRIO antibody (AA 1961-2070) (ABIN563257)

Target: TRIO (Triple Functional Domain Protein (TRIO))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This TRIO antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRIO Antibody

Binding Specificity: AA 1961-2070

Purpose: Mouse polyclonal antibody raised against a partial recombinant TRIO.

Sequence: ERKSSSLKRR HYVLQELVET ERDYVRDLGY VVEGYMALMK EDGVPDDMKG KDKIVFGNIH QIYDWHRDFF LGELEKCLED PEKLGSLFVK HERRLHMYIA YCQNKPKSEH

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TRIO (NP_009049, 1961 a.a. ~ 2070 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TRIO antibody (ABIN563257)

Wang, Fang, Qu, Cao, Zhou, Deng: "Upregulated TRIO expression correlates with a malignant phenotype in human hepatocellular carcinoma." in: Tumour biology, (2015) (PubMed).

van Rijssel, Kroon, Hoogenboezem, van Alphen, de Jong, Kostadinova, Geerts, Hordijk, van Buul: "The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation." in: Molecular biology of the cell, Vol. 23, Issue 15, pp. 2831-44, (2012) (PubMed).

Yano, Yamazaki, Adachi, Okawa, Fort, Uji, Tsukita, Tsukita: "Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling." in: The Journal of cell biology, Vol. 193, Issue 2, pp. 319-32, (2011) (PubMed).

Target Details for TRIO

Target: TRIO (Triple Functional Domain Protein (TRIO))

Alternative Name: TRIO

Background: Full Gene Name: triple functional domain (PTPRF interacting)
Synonyms: FLJ42780,tgat

Gene ID: 7204

NCBI Accession: NM_007118