anti-Tryptase alpha/beta 1 (TPSAB1) Antibodies

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Additionally we are shipping Tryptase alpha/beta 1 Kits (81) and Tryptase alpha/beta 1 Proteins (32) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TPSAB1 7177 Q15661 , P20231
TPSAB1 100503895 Q02844
TPSAB1 54271 P27435
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Top anti-Tryptase alpha/beta 1 Antibodies at antibodies-online.com

Showing 10 out of 152 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Mast Cell Tryptase was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- Mast Cell Tryptase Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). Western blot analysis of Mast Cell Tryptase expression in 293T whole cell lysates ( Lane 1). Mast Cell Tryptase at 30KD was detected using rabbit anti- Mast Cell Tryptase Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cat Mouse Un-conjugated EIA, IHC (fro), IF, IHC (p), WB   0.2 mg Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IF, IHC, IHC (fro), IHC (p), WB Immunohistochemistry-Paraffin: Tryptase alpha/TPS1 Antibody (AA1)  - Human tonsil stained with Mast Cell Tryptase antibody. 0.25 mL Log in to see 7 to 9 Days
$446.35
Details
Cat Mouse Un-conjugated EIA, IHC (fro), IHC (p), WB   20 μg Log in to see 6 to 8 Days
$225.50
Details
Cat Mouse Un-conjugated ELISA, IHC (fro), IHC (p), WB Immunohistochemistry-Paraffin: Tryptase alpha/TPS1 Antibody (3H2643) [NBP1-40202] - Analysis of anti-TPSAB1 / Mast Cell Tryptase antibody with human lung at concentration 5 ug/ml. 0.05 mg Log in to see 10 to 13 Days
$559.35
Details
Human Rabbit Un-conjugated EIA, WB TPSAB1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the TPSAB1 antibody detected the TPSAB1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Mouse Intestine Tissue. 100 μg Log in to see 15 to 18 Days
$332.00
Details
Mouse Rabbit Un-conjugated WB TPSAB1 Antibody (C-term) (ABIN656204) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the TPSAB1 antibody detected the TPSAB1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated FACS, WB TPSAB1 Antibody (Center) (ABIN651632) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the TPSAB1 antibody detected the TPSAB1 protein (arrow). TPSAB1 Antibody (Center) (ABIN651632) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: TPSAB1 Antibody (SC68-07)  - Analysis of paraffin-embedded human lung tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin. Immunohistochemistry-Paraffin: TPSAB1 Antibody (SC68-07)  - Analysis of paraffin-embedded human tonsil tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin. 100 μL Log in to see 34 Days
$375.73
Details

Top referenced anti-Tryptase alpha/beta 1 Antibodies

  1. Human Monoclonal TPSAB1 Primary Antibody for ELISA, FACS - ABIN4363027 : Haase, Klawitter, Baretton: IkappaBgamma is expressed in mast cells. in Virchows Archiv : an international journal of pathology 2004 (PubMed)
    Show all 9 Pubmed References

  2. Cat (Feline) Monoclonal TPSAB1 Primary Antibody for ELISA, IHC (fro) - ABIN450240 : Galiazzo, Giancola, Stanzani, Fracassi, Bernardini, Forni, Pietra, Chiocchetti: Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract. in Histochemistry and cell biology 2018 (PubMed)

More Antibodies against Tryptase alpha/beta 1 Interaction Partners

Human Tryptase alpha/beta 1 (TPSAB1) interaction partners

  1. Basal serum tryptase in children with actual drug hypersensitivity is not a risk factor for severe systemic reactions

  2. Increased TPSAB1 copy number is associated with multisystem disorder.

  3. this study shows that active cow's milk-induced enterocolitis syndrome children have higher serum tryptase levels compared to resolved disease

  4. sBT levels may have a potential use in supporting a diagnosis of asthma in children and as a predictor of disease severity.

  5. CD3 showed a positive correlation with tryptase and microvascular density, while multiple regression analysis efficaciously predicted microvascular density depending on CD3 and tryptase as predictors, supporting a complex interplay between these cells in sustaining tumor angiogenesis in Diffuse large B cell lymphoma patients.

  6. We found the determination of serum tryptase levels over time to be a reassuring correlate of clinical improvement in pediatric mastocytosis

  7. genetic polymorphism is associated with Dengue Hemorrhagic Fever and Dengue Shock Syndrome in Vietnam and Philippines

  8. Elevated serum tryptase and ET-1 may be markers of increased coronary instability; some cytokines may be related to the extension of CAD.

  9. these data suggest that the expression of tryptase is regulated by SCF/C-KIT signaling via the ERK1/2 and p38MAPK pathways.

  10. Urine tryptase beta was increased in patients with chronic prostatitis/chronic pelvic pain syndrome compared to controls.

  11. Results demonstrated serum tryptase levels in colo-rectal cancer (CRC) patients before radical surgical resection.

  12. Circulating tryptase level is associated to obesity related parameters and has a close relation with various metabolic risk factors for subclinical atherosclerosis

  13. Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma.

  14. The best criterion for discriminating IgE- and non IgE-mediated hypersensitivity reactions in anaesthesia was a tryptase value exceeding twice the basal one.

  15. With elevated tryptase level, a history of hornet sting-triggered anaphylaxis, and venom-specific IgE, a patient is at increased risk of severe life-threatening anaphylactic response to a future sting, as well as for having underlying clonal mastocytosis.

  16. Monitoring of serum baseline tryptase in indolent systemic mastocytosis patients is closely associated with poor prognosis disease features as well as with disease progression.

  17. The accumulated data in this review suggest that mast cells and their tryptases and chymases play important roles in tissue repair.

  18. The high density of tryptase(+) Mmast cells at invasive margins of tumours was associated with advanced stages of colorectal cancer and was strongly correlated with PAR-2 expression.

  19. As much as 82% of the variation in serum tryptase is due to genetics factors, and genetic effects overlap serum tryptase and body mass index.

  20. The identification of an abundant population of tryptase(+)/Nanog(+) cells in infantile haemangioma is novel.

Mouse (Murine) Tryptase alpha/beta 1 (TPSAB1) interaction partners

  1. Following TNFalpha treatment, increased elastase and tryptase modify the balance between activation and deactivation, elevating active chemerin concentration in adipocyte media and subsequent CMKLR1 activation.

  2. transcriptional activation of mouse mast cell Protease-7 by activin and transforming growth factor-beta is inhibited by microphthalmia-associated transcription factor

  3. Because mMCP-6 and mMCP-7 can compensate for each other in this mouse disease model, the elimination of both tryptases is necessary to reveal the prominent roles of these serine proteases in joint inflammation and destruction.

  4. TGF-beta stimulates mmcp-7 transcription through the Smad3-Smad4 pathway as well as c-fos induction

Tryptase alpha/beta 1 (TPSAB1) Antigen Profile

Protein Summary

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells\; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Gene names and symbols associated with TPSAB1

  • tryptase alpha/beta 1 (TPSAB1) antibody
  • tryptase (MCT7) antibody
  • tryptase alpha/beta 1 (tpsab1) antibody
  • tryptase alpha/beta 1 (Tpsab1) antibody
  • Mcp-7 antibody
  • Mcp7 antibody
  • Mcpt7 antibody
  • MMCP-7 antibody
  • PMCT7 antibody
  • rMCP-7 antibody
  • TPS1 antibody
  • TPS2 antibody
  • tpsab1 antibody
  • TPSB1 antibody

Protein level used designations for TPSAB1

mast cell alpha II tryptase , mast cell beta I tryptase , tryptase I , tryptase alpha II , tryptase alpha-1 , tryptase alpha/beta-1 , tryptase beta 1 , tryptase beta I , tryptase beta-1 , tryptase-1 , tryptase-I , tryptase-III , tryptase alpha/beta 1 , mast cell protease 7 , mast cell-restricted serine protease 7 , tryptase , MMCP-7 , tryptase, skin

GENE ID SPECIES
7177 Homo sapiens
397389 Sus scrofa
497002 Xenopus (Silurana) tropicalis
100503895 Mus musculus
54271 Rattus norvegicus
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