Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Proteins
The protein encoded by TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
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Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) protein (His-DYKDDDDK-Strep II Tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 1-239) protein (rho-1D4 tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) protein (His tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 68-239) protein (His tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 1-234) protein (rho-1D4 tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) protein (His tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234), (Extracellular Domain) (Active) protein (Fc Tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 1-234) protein (GST tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 153-234) protein (GST tag) Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) (AA 63-234) Protein Protein
Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8) Protein Profile
Protein Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
Gene names and symbols associated with TNFSF8
- tumor necrosis factor (ligand) superfamily, member 8 (Tnfsf8) antibody
- TNF superfamily member 8 (TNFSF8) antibody
- tumor necrosis factor superfamily member 8 (TNFSF8) antibody
- TNF superfamily member 8 (Tnfsf8) antibody
- CD30L antibody
- CD30LG antibody
- CD153 antibody
- TNFRSF8 antibody
- TNFSF8 antibody
Protein level used designations for TNFSF8
CD30 ligand , CD30-L , tumor necrosis factor ligand superfamily member 8 , CD153 antigen , CD30 antigen ligand , tumor necrosis factor receptor superfamily, member 8 , tumor necrosis factor (ligand) superfamily, member 8 , tumor necrosis factor superfamily member 8
GENE ID | SPECIES |
---|---|
21949 | Mus musculus |
944 | Homo sapiens |
574056 | Bos taurus |
378930 | Gallus gallus |
464686 | Pan troglodytes |
612608 | Canis lupus familiaris |
683163 | Rattus norvegicus |
702944 | Macaca mulatta |
100735796 | Cavia porcellus |
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