anti-Ubiquitin Specific Peptidase 37 (USP37) Antibodies

Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Additionally we are shipping USP37 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP37 57695 Q86T82
USP37 319651 Q8C0R0
USP37    
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Top anti-USP37 Antibodies at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-USP37 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB UBP37 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the UBP37 antibody detected the UBP37 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: USP37 Antibody [ABIN2582909] - FFPE section of human prostate carcinoma. Affinity purified rabbit anti-USP37 used at a dilution of 1:250. 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: USP37 Antibody  - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus & nucleoli. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IHC, IP 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated WB Western blot analysis of USP37 expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$295.00
Details
Human Rabbit Un-conjugated WB USP37 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Dog Rabbit Un-conjugated IF, IP, IHC (p)   100 μL Log in to see 7 to 9 Days
$595.83
Details

USP37 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-USP37 Antibodies

  1. Human Polyclonal USP37 Primary Antibody for ICC, IF - ABIN258290 : Das, Taylor, Gireud, Singh, Lee, Fuller, Ji, Fangusaro, Rajaram, Goldman, Eberhart, Gopalakrishnan: The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation. in Oncogene 2013 (PubMed)

  2. Human Polyclonal USP37 Primary Antibody for ICC, IF - ABIN4364592 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against USP37 Interaction Partners

Human Ubiquitin Specific Peptidase 37 (USP37) interaction partners

  1. USP37 interacts with Cdt1 (show CDT1 Antibodies) and is able to de-ubiquitinate Cdt1 (show CDT1 Antibodies) in vivo and, USP37 is able to regulate the loading of MCM complexes onto the chromatin.

  2. USP37 associates with cohesin and contributes to sister chromatid resolution. Cohesion defects are rescued by expression of an RNAi-resistant USP37, but not the catalytically impaired USP37(C350A) mutant.

  3. USP37 is significantly upregulated in human lung cancer tissues, where its expression is positively correlated with c-Myc (show MYC Antibodies) protein expression.

  4. These results suggested that the UIMs in USP37 contribute to the full enzymatic activity, but not ubiquitin chain substrate specificity, of USP37 possibly by holding the ubiquitin chain substrate in the proximity of the catalytic core.

  5. our findings of USP37-modulating PLZF (show ZBTB16 Antibodies)/RARA (show RARA Antibodies) stability and cell transformation suggest that USP37 is a potential therapeutic target for PLZF (show ZBTB16 Antibodies)/RARA (show RARA Antibodies)-associated APL (show FASL Antibodies)

  6. USP37 links REST to the control of p27 (show PAK2 Antibodies) stability and cell proliferation.

  7. Skp1 (show SKP1 Antibodies)-Cul1 (show CUL1 Antibodies)-F-box ubiquitin ligase (SCF (show KITLG Antibodies)(betaTrCP (show BTRC Antibodies)))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry

  8. The deubiquitinase USP37 binds CDH1 (show CDH1 Antibodies) and removes degradative polyubiquitin (show UBB Antibodies) from cyclin A (show CCNA2 Antibodies). USP37 was induced by E2F (show E2F1 Antibodies) factors in G1, peaked at G1/S, and was degraded in late mitosis. Phosphorylation of USP37 by CDK2 (show CDK2 Antibodies) stimulated its full activity.

USP37 Antigen Profile

Protein Summary

Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'- linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-630 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (By similarity).

Gene names and symbols associated with USP37

  • ubiquitin specific peptidase 37 (USP37) antibody
  • ubiquitin specific peptidase 37 (usp37) antibody
  • ubiquitin specific peptidase 37 (Usp37) antibody
  • 4932415L06Rik antibody
  • C330008N13Rik antibody
  • wu:fi15b04 antibody
  • wu:fi38d03 antibody
  • zgc:152882 antibody
  • zgc:153999 antibody

Protein level used designations for USP37

ubiquitin specific peptidase 37 , ubiquitin specific protease 37 , ubiquitin carboxyl-terminal hydrolase 37-like , deubiquitinating enzyme 37 , tmp_locus_50 , ubiquitin carboxyl-terminal hydrolase 37 , ubiquitin thioesterase 37 , ubiquitin thiolesterase 37 , ubiquitin-specific-processing protease 37 , Deubiquitinating enzyme 37 , Ubiquitin carboxyl-terminal hydrolase 37 , Ubiquitin thiolesterase 37 , Ubiquitin-specific-processing protease 37 , fi15b04 , usp39

GENE ID SPECIES
459944 Pan troglodytes
701732 Macaca mulatta
100124313 Xenopus (Silurana) tropicalis
100155158 Sus scrofa
100347231 Oryctolagus cuniculus
100389662 Callithrix jacchus
100481404 Ailuropoda melanoleuca
100541053 Meleagris gallopavo
100602108 Nomascus leucogenys
57695 Homo sapiens
319651 Mus musculus
407168 Bos taurus
488523 Canis lupus familiaris
424216 Gallus gallus
768201 Danio rerio
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