anti-Ubiquitin-Conjugating Enzyme E2B (UBE2B) Antibodies

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping UBE2B Proteins (22) and UBE2B Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBE2B 7320 P63146
UBE2B 81816 P63149
UBE2B 22210 P63147
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Top anti-UBE2B Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) . Dilution: 1:500~1000 Western Blot analysis of UBE2B expression in transfected 293T cell line by UBE2B monoclonal antibody (M06), clone 4C3.Lane 1: UBE2B transfected lysate(17.3 KDa).Lane 2: Non-transfected lysate. Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of UBE2B (arrow) using rabbit polyclonal UBE2B Antibody (E132) (ABIN388848). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the UBE2B gene. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: HR6B/UBE2B Antibody [NBP1-31293] - A. 30 ug 293T whole cell lysate/extract B. 30 ug whole cell lysate/extract of 3xFlag-human UBE2B-transfected 293T cells. Used at a dilution of 1:5000. Western Blot: HR6B/UBE2B Antibody [NBP1-31293] - Sample (30 ug of whole cell lysate) A: Hela 12% SDS PAGE UBE2B antibody diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated WB Western Blot: Ube2B Antibody [NBP2-20781] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 12% SDS PAGE gel, diluted at 1:1000. Western Blot: HR6B/UBE2B Antibody  - Mouse tissue extract (50 ug) was separated by 15% SDS-PAGE, and the membrane was blotted with UBE2B antibody diluted at 1:500. The signal was developed with Trident ECL plus-Enhanced. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat lung using UBE2B antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
$334.77
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Mouse Un-conjugated WB Western Blot: HR6B/UBE2B Antibody (1E11) [NBP2-46262] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UBE2B. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using UBE2B antibody (ABIN5973734) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat lung using UBE2B Antibody (ABIN5973734) at dilution of 1/100 (40x lens). 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Mouse Un-conjugated WB Western Blot analysis of UBE2B expression in transfected 293T cell line by UBE2B MaxPab polyclonal antibody.<br><br>Lane 1: UBE2B transfected lysate(16.72 KDa).<br>Lane 2: Non-transfected lysate.<br> UBE2B MaxPab polyclonal antibody. Western Blot analysis of UBE2B expression in Jurkat. 50 μL Log in to see 11 to 12 Days
$440.00
Details

More Antibodies against UBE2B Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2B (UBE2B) interaction partners

  1. RAD6 is upregulated in response to chemotherapy and significantly correlated with expression of ovarian cancer (OC) stem cell signaling genes ALDH1A1 (show ALDH1A1 Antibodies) and SOX2 (show SOX2 Antibodies) and poor prognosis of OC patients.

  2. These results point to an important role of the affinity between RNF4 (show RNF4 Antibodies) and its cognate RAD6B or UBCH5B (show UBE2D2 Antibodies) in governing the multiplicity of substrate ubiquitination.

  3. RAD6 promotes proteasome activity and nuclear translocation by enhancing the degradation of PSMF1 (show PSMF1 Antibodies) and the lamin B receptor (show LBR Antibodies).

  4. In conclusion, we reveal that miR (show MLXIP Antibodies)-455-5p expression is regulated by the TGF-beta (show TGFB1 Antibodies)-dependent pathway, which subsequently leads to UBE2B down-regulation and contributes to oral cancer tumourigenesis.

  5. Data show that the ubiquitin-conjugating enzyme E2 RAD6A/B-MDM2 ubiquitin ligase machinery regulates anti-silencing function 1A protein (ASF1A) degradation.

  6. A novel variant (Chr5.133706925 A > G) residing in the UBE2B gene promoter region confers a high risk for idiopathic azoospermia in a Chinese population.

  7. RAD6 physically interacts with heterochromatin protein 1alpha and ubiquitinates HP1alpha (show CBX5 Antibodies) at residue K154, thereby promoting heterochromatin protein 1alpha degradation through the autophagy pathway

  8. UBE2B mRNA alterations are associated with severe oligozoospermia in infertile men.

  9. RNF168 (show RNF168 Antibodies), in complex with RAD6A (show ube2a Antibodies) or RAD6B, is activated in the DNA-damage-induced protein ubiquitination cascade.

  10. UBE2B polymorphisms g.-293T>G, g.20016A>G and g.9157A>G are not associated with male infertility, and the GA haplotype is likely a protective factor for male fertility in Northeast Chinese men.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2B (UBE2B) interaction partners

  1. RNF168 (show RNF168 Antibodies), in complex with RAD6A (show ube2a Antibodies) or RAD6B, is activated in the DNA-damage-induced protein ubiquitination cascade.

  2. These results suggest that Ube2b, as a direct androgen receptor transcriptional target in Sertoli cells, mediates the function of androgen recpetor in spermatogenesis by promoting H2A ubiquitylation.

  3. HR6B represses major satellite repeat transcription in spermatocytes, and functions in the maintenance of X chromosome silencing in spermatocytes and spermatids.

  4. The present findings reveal a specific requirement for the ubiquitin-conjugating activity of HR6B in relation to dynamic aspects of the synaptonemal complex and meiotic recombination in spermatocytes.

  5. Ube2b deficient mice are shown to present male infertility and sperm head shape anomalies.

  6. HR6B exerts control over different histone modifications in spermatocytes and spermatids, and that this function contributes to the postmeiotic maintenance of X chromosome silencing.

UBE2B Antigen Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Gene names and symbols associated with UBE2B

  • ubiquitin conjugating enzyme E2 B (UBE2B) antibody
  • ubiquitin-conjugating enzyme E2B (Ube2b) antibody
  • ubiquitin conjugating enzyme E2 B (ube2b) antibody
  • ubiquitin-conjugating enzyme E2B (RAD6 homolog) (ube2b) antibody
  • ubiquitin conjugating enzyme E2 B S homeolog (ube2b.S) antibody
  • 2610301N02Rik antibody
  • E2-14k antibody
  • e2-17kda antibody
  • hhr6b antibody
  • hr6b antibody
  • mHR6B antibody
  • Rad6b antibody
  • ubc2 antibody
  • zgc:100921 antibody

Protein level used designations for UBE2B

E2 protein , RAD6 homolog B , ubiquitin carrier protein B , ubiquitin-conjugating enzyme E2 B , ubiquitin-conjugating enzyme E2-17 kDa , ubiquitin-conjugating enzyme E2B (RAD6 homolog) , ubiquitin-protein ligase B , E2(14k) , ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme E2(14k) , ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae) , ubiquitin-conjugating enzyme E2B, RAD6 homolog , ubiquitin-conjugating enzyme E2B, RAD6 homology , HR6B , ubiquitin conjugating-protein , Ubiquitin-conjugating enzyme E2 B , ubiquitin-conjugating enzyme E2 , E214K

GENE ID SPECIES
7320 Homo sapiens
512207 Bos taurus
474683 Canis lupus familiaris
81816 Rattus norvegicus
100009132 Oryctolagus cuniculus
448706 Xenopus (Silurana) tropicalis
462065 Pan troglodytes
100286422 Salmo salar
100301680 Oncorhynchus mykiss
437020 Danio rerio
443745 Xenopus laevis
710678 Macaca mulatta
100381250 Ovis aries
22210 Mus musculus
100513527 Sus scrofa
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