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Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
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Dog (Canine) Polyclonal UBE2E2 Primary Antibody for IHC, WB - ABIN2781267
Plafker, Plafker, Weissman, Macara: Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import. in The Journal of cell biology 2004
Show all 2 Pubmed References
changes in methylation rates in umbilical cord samples were associated with the proportion of Firmicutes in the maternal gut (show GUSB Antibodies)
We investigated the modification of air pollution and diabetes association by a genetic risk score covering 63 T2D genes. Five single variants near GRB14 (show GRB14 Antibodies), UBE2E2, PTPRD (show PTPRD Antibodies), VPS26A (show VPS26A Antibodies) and KCNQ1 (show KCNQ1 Antibodies) showed nominally significant interactions with PM10 (P<0.05). Our results suggest that genetic risk for T2D may modify susceptibility to air pollution through alterations in insulin (show INS Antibodies) sensitivity.
Ube2e2 underexpression is associated with metabolic diseases.
After adjustment for age, sex, and BMI, rs163182 in KCNQ1 and rs7612463 in UBE2E2 were found to be associated with Type 2 Diabetes Mellitus risk in Chinese Han population.
rs7612463 UBE2E2 single nucleotide polymorphism is associated with type 2 diabetes mellitus in a Chinese Han population.
Study found lack of association between UBE2E2 gene polymorphism (rs7612463) and type 2 diabetes mellitus in a Saudi population
The genetic variants of UBE2E2 are associated with gestational diabetes mellitus and fasting blood glucose.
Single nucleotide polymorphism in UBE2E2 is associated with type 2 diabetes.
Siah proteins function as E3 ubiquitin-protein ligases
Ubc8 (show UBE2H Antibodies) is a major ISG15 (show ISG15 Antibodies)-conjugating enzyme responsible for protein ISGylation upon interferon (show IFNA Antibodies) stimulation
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination (By similarity).
ubiquitin-conjugating enzyme E2 E2
, ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
, ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog)
, ubiquitin-conjugating enzyme E2E 2
, ubiquitin carrier protein E2
, ubiquitin-conjugating enzyme E2E 2 (homologous to yeast UBC4/5)
, ubiquitin-protein ligase E2
, TBC1 domain family, member 12