UBE2E2 antibody (AA 1-201)

Catalog No. ABIN7271177

The Rabbit Polyclonal anti-UBE2E2 antibody is suitable to detect UBE2E2 in samples from Human. It has been validated for WB.

Quick Overview for UBE2E2 antibody (AA 1-201) (ABIN7271177)

Target: UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2E2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBE2E2 Antibody

Binding Specificity: AA 1-201

Purpose: UBE2E2 Rabbit pAb

Sequence: MSTEAQRVDD SPSTSGGSSD GDQRESVQQE PEREQVQPKK KEGKISSKTA AKLSTSAKRI QKELAEITLD PPPNCSAGPK GDNIYEWRST ILGPPGSVYE GGVFFLDITF SPDYPFKPPK VTFRTRIYHC NINSQGVICL DILKDNWSPA LTISKVLLSI CSLLTDCNPA DPLVGSIATQ YMTNRAEHDR MARQWTKRYA T

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human UBE2E2 (NP_689866.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBE2E2

Target: UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))

Alternative Name: UBE2E2

Background: Ube2E2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 96 % identical amino acid sequence with Ube2E1 and Ube2E3 with the exception of the N-terminal extension that has little in common with the other two E2s. Ube2E2 interacts with ARA54 and RNF8. The RNF8/ Ube2E2 interaction is found to catalyze K48-linked poly-ubiquitination. Ube2E2 may play a role in ubiquitination and subsequent proteasomal degradation of the E3 Ub ligase Parkin.,UBE2E2,UBCH8,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBE2E2

Molecular Weight: 22kDa

Gene ID: 7325

UniProt: Q96LR5