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anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Antibodies

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2L 6 Proteins (16) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBE2L6 9246 O14933
UBE2L6 56791 Q9QZU9
UBE2L6 295704 Q4V8J2
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Top anti-Ubiquitin-Conjugating Enzyme E2L 6 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UBE2L6 Antibody Positive Control: Lane1: 70ug U6A lysate, Lane, 2: 70ug IFN-g stimulated U6A lysate Primary Antibody Dilution : 1:2000 Secondary Antibody : Anti-rabbit-HRP Secondry Antibody Dilution : 1:5000 Submitted by: Torsten Ginter & Dr. Oliver Kramer, Institute for Biochemistry and Biophysicws, Center for Biomedicine, Friedrich-Schiller University WB Suggested Anti-UBE2L6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Small Intestine 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UBE2L6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB Human Spleen (formalin-fixed, paraffin-embedded) stained with UBE2L6 antibody ABIN364358 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Thymus (formalin-fixed, paraffin-embedded) stained with UBE2L6 antibody ABIN364358 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 11 to 14 Days
$563.44
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB The UBE2L6 Antibody (C-term) (ABIN388854) is used in Western blot to detect UBE2L6 in HL-60 cell lysate. Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody (C-term)(ABIN388854), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis UBE2L6 using K562 whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.4 mL Log in to see 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, IP, WB 100 μg Log in to see 14 to 16 Days
$247.82
Details

Top referenced anti-Ubiquitin-Conjugating Enzyme E2L 6 Antibodies

  1. Human Polyclonal UBE2L6 Primary Antibody for IHC (p), WB - ABIN1882146 : Kumar, Kao, Howley: Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal UBE2L6 Primary Antibody for IHC (p), WB - ABIN388854 : Krämer, Müller, Buchwald, Reichardt, Heinzel: Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 (PubMed)
    Show all 4 Pubmed References

  3. Monoclonal UBE2L6 Primary Antibody for ELISA, WB - ABIN533787 : Moynihan, Ardley, Nuber, Rose, Jones, Markham, Scheffner, Robinson: The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal UBE2L6 Primary Antibody for ELISA, WB - ABIN563994 : Zhang, Adyshev, Singleton, Li, Cepeda, Huang, Zou, Verin, Tu, Garcia, Ye: Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. in FEBS letters 2008 (PubMed)

  5. Cow (Bovine) Polyclonal UBE2L6 Primary Antibody for WB - ABIN2775688 : Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8. in Molecular and cellular biochemistry 2006 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2L 6 Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. Depletion of either ISG15 or UBE2L6/UBCH8 resulted in enhanced endogenous autophagic flux.

  2. Data indicate that reduced expression of the ubiquitin-conjugating enzyme UbcH8 protein correlated with poor outcome in nasopharyngeal carcinoma (NPC) patients.

  3. study reports that UBCH8 and UBE2G1 and UBE2G2 cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 and Cdt1, respectively

  4. gain and loss-of-function approaches show that UBCH8 and the ubiquitin-ligase SIAH1 physically interact with and target FLT3-ITD for proteasomal degradation

  5. The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin.

  6. Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 knockdown, respectively.

  7. Ube1L was required for transfer of ISG15 to UbcH8 and for binding of Ube1L to UbcH8

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. we have identified a loss-of-function mutation in Ube2l6 that contributes to the chromosome 2 obesity quantitative trait locus.

  2. Ubc8 is a major ISG15-conjugating enzyme responsible for protein ISGylation upon interferon stimulation

Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Antigen Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with UBE2L6

  • ubiquitin conjugating enzyme E2 L6 (UBE2L6) antibody
  • ubiquitin-conjugating enzyme E2L 6 (Ube2l6) antibody
  • 2810489I21Rik antibody
  • RIG-B antibody
  • Ubce8 antibody
  • UBCH8 antibody
  • UbcM8 antibody
  • UBE2L6 antibody

Protein level used designations for UBE2L6

ubiquitin-conjugating enzyme E2L 6 , ubiquitin/ISG15-conjugating enzyme E2 L6 , retinoic acid induced gene B protein , retinoic acid-induced gene B protein , ubiquitin carrier protein L6 , ubiquitin-protein ligase L6 , E2 ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme 8 , ubcM8 , Ubiquitin carrier protein L6 , Ubiquitin-protein ligase L6

GENE ID SPECIES
466588 Pan troglodytes
475967 Canis lupus familiaris
100349814 Oryctolagus cuniculus
100514753 Sus scrofa
9246 Homo sapiens
56791 Mus musculus
295704 Rattus norvegicus
509471 Bos taurus
Selected quality suppliers for anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Antibodies
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