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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2L 6 Proteins (15) and and many more products for this protein.
Showing 10 out of 81 products:
Human Polyclonal UBE2L6 Primary Antibody for IHC (p), WB - ABIN1882146
Kumar, Kao, Howley: Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. in The Journal of biological chemistry 1997
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Human Polyclonal UBE2L6 Primary Antibody for IHC (p), WB - ABIN388854
Krämer, Müller, Buchwald, Reichardt, Heinzel: Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008
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Cow (Bovine) Polyclonal UBE2L6 Primary Antibody for WB - ABIN2775688
Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8. in Molecular and cellular biochemistry 2006
Monoclonal UBE2L6 Primary Antibody for ELISA, WB - ABIN533787
Moynihan, Ardley, Nuber, Rose, Jones, Markham, Scheffner, Robinson: The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1. in The Journal of biological chemistry 1999
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Human Monoclonal UBE2L6 Primary Antibody for ELISA, WB - ABIN563994
Zhang, Adyshev, Singleton, Li, Cepeda, Huang, Zou, Verin, Tu, Garcia, Ye: Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. in FEBS letters 2008
Depletion of either ISG15 or UBE2L6/UBCH8 resulted in enhanced endogenous autophagic flux.
Data indicate that reduced expression of the ubiquitin-conjugating enzyme UbcH8 protein correlated with poor outcome in nasopharyngeal carcinoma (NPC) patients.
study reports that UBCH8 and UBE2G1 and UBE2G2 cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 and Cdt1, respectively
gain and loss-of-function approaches show that UBCH8 and the ubiquitin-ligase SIAH1 physically interact with and target FLT3-ITD for proteasomal degradation
The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin.
Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 knockdown, respectively.
Ube1L was required for transfer of ISG15 to UbcH8 and for binding of Ube1L to UbcH8
we have identified a loss-of-function mutation in Ube2l6 that contributes to the chromosome 2 obesity quantitative trait locus.
Ubc8 is a major ISG15-conjugating enzyme responsible for protein ISGylation upon interferon stimulation
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
ubiquitin-conjugating enzyme E2L 6
, ubiquitin/ISG15-conjugating enzyme E2 L6
, retinoic acid induced gene B protein
, retinoic acid-induced gene B protein
, ubiquitin carrier protein L6
, ubiquitin-protein ligase L6
, E2 ubiquitin conjugating enzyme
, ubiquitin-conjugating enzyme 8
, Ubiquitin carrier protein L6
, Ubiquitin-protein ligase L6