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anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Antibodies

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2L 6 Proteins (15) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBE2L6 9246 O14933
UBE2L6 56791 Q9QZU9
UBE2L6 295704 Q4V8J2
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Top anti-Ubiquitin-Conjugating Enzyme E2L 6 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB The UBE2L6 Antibody (C-term) (ABIN388854) is used in Western blot to detect UBE2L6 in HL-60 cell lysate. Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody (C-term)(ABIN388854), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UBE2L6 Antibody Positive Control: Lane1: 70ug U6A lysate, Lane, 2: 70ug IFN-g stimulated U6A lysate Primary Antibody Dilution : 1:2000 Secondary Antibody : Anti-rabbit-HRP Secondry Antibody Dilution : 1:5000 Submitted by: Torsten Ginter & Dr. Oliver Kramer, Institute for Biochemistry and Biophysicws, Center for Biomedicine, Friedrich-Schiller University WB Suggested Anti-UBE2L6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Small Intestine 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UBE2L6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: UbcH8/Ube2L6 Antibody (k1H3) [NBP1-04351] - Ube2L6 Antibody (k1H3) [NBP1-04351]-Paraffin embedded sections of human breast lobule tissue were incubated with anti-human UBE2L6 for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB) Western Blot: UbcH8/Ube2L6 Antibody (k1H3) [NBP1-04351] - Ube2L6 Antibody (k1H3) [NBP1-04351]-Cell lysates of MCF7 (20ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human UBE2L6 . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Log in to see 12 to 15 Days
$415.44
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.4 mL Log in to see 8 to 11 Days
$517.00
Details
Human Rabbit Un-conjugated ELISA, IP, WB 100 μg Log in to see 20 to 21 Days
$218.90
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of Jurkat cell line, using UBE2L6 antibody. 100 μL Log in to see 16 Days
$357.62
Details

Top referenced anti-Ubiquitin-Conjugating Enzyme E2L 6 Antibodies

  1. Human Polyclonal UBE2L6 Primary Antibody for IHC (p), WB - ABIN1882146 : Kumar, Kao, Howley: Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal UBE2L6 Primary Antibody for IHC (p), WB - ABIN388854 : Krämer, Müller, Buchwald, Reichardt, Heinzel: Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal UBE2L6 Primary Antibody for ELISA, WB - ABIN563994 : Zhang, Adyshev, Singleton, Li, Cepeda, Huang, Zou, Verin, Tu, Garcia, Ye: Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury. in FEBS letters 2008 (PubMed)

  4. Cow (Bovine) Polyclonal UBE2L6 Primary Antibody for WB - ABIN2775688 : Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8. in Molecular and cellular biochemistry 2006 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2L 6 Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. Depletion of either ISG15 (show ISG15 Antibodies) or UBE2L6/UBCH8 resulted in enhanced endogenous autophagic flux.

  2. Data indicate that reduced expression of the ubiquitin-conjugating enzyme (show Ube2t Antibodies) UbcH8 (show UBE2E2 Antibodies) protein correlated with poor outcome in nasopharyngeal carcinoma (NPC (show NPC1 Antibodies)) patients.

  3. study reports that UBCH8 (show UBE2E2 Antibodies) and UBE2G1 (show Ube2g1 Antibodies) and UBE2G2 (show UBE2G2 Antibodies) cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 (show CDKN1A Antibodies) and Cdt1 (show CDT1 Antibodies), respectively

  4. gain and loss-of-function approaches show that UBCH8 (show UBE2E2 Antibodies) and the ubiquitin-ligase SIAH1 physically interact with and target FLT3 (show FLT3 Antibodies)-ITD for proteasomal degradation

  5. The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin.

  6. Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 (show BRCA2 Antibodies) knockdown, respectively.

  7. Ube1L (show UBA7 Antibodies) was required for transfer of ISG15 (show ISG15 Antibodies) to UbcH8 (show UBE2E2 Antibodies) and for binding of Ube1L (show UBA7 Antibodies) to UbcH8 (show UBE2E2 Antibodies)

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. we have identified a loss-of-function mutation in Ube2l6 that contributes to the chromosome 2 obesity quantitative trait locus (show MC3R Antibodies).

  2. Ubc8 is a major ISG15-conjugating enzyme responsible for protein ISGylation upon interferon stimulation

Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Antigen Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with UBE2L6

  • ubiquitin conjugating enzyme E2 L6 (UBE2L6) antibody
  • ubiquitin-conjugating enzyme E2L 6 (Ube2l6) antibody
  • 2810489I21Rik antibody
  • RIG-B antibody
  • Ubce8 antibody
  • UBCH8 antibody
  • UbcM8 antibody
  • UBE2L6 antibody

Protein level used designations for UBE2L6

ubiquitin-conjugating enzyme E2L 6 , ubiquitin/ISG15-conjugating enzyme E2 L6 , retinoic acid induced gene B protein , retinoic acid-induced gene B protein , ubiquitin carrier protein L6 , ubiquitin-protein ligase L6 , E2 ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme 8 , ubcM8 , Ubiquitin carrier protein L6 , Ubiquitin-protein ligase L6

GENE ID SPECIES
466588 Pan troglodytes
475967 Canis lupus familiaris
100349814 Oryctolagus cuniculus
100514753 Sus scrofa
9246 Homo sapiens
56791 Mus musculus
295704 Rattus norvegicus
509471 Bos taurus
Selected quality suppliers for anti-Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Antibodies
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