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Vpx Protein Proteins

Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells.

3 results:

Vpx Protein (VPX) (AA 1-112), (full length) protein (His-SUMO Tag) Protein

VPX Origin: Simian Immunodeficiency Virus (SIV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710778
$917.40
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 11 Business Days

Vpx Protein (VPX) (AA 1-113), (full length) protein (His tag) Protein

VPX Origin: Human Immunodeficiency Virus (HIV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710828
$917.40
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 11 Business Days

Vpx Protein (VPX) (AA 1-112), (full length) protein (His-SUMO Tag) Protein

VPX Origin: Simian Immunodeficiency Virus (SIV) Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710812
$917.40
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
  • Type Protein
    • Protein
  • Target Vpx Protein (VPX)
    • Vpx Protein (VPX)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Interleukin 8 (IL8)
    • Leptin (LEP)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • SARS-CoV-2 Spike S1
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
  • Application
    • SDS-PAGE (SDS)
  • Reactivity
    • Simian Immunodeficiency Virus (SIV)
    • Human Immunodeficiency Virus (HIV)
  • Images available
  • Host
    • Escherichia coli (E. coli)
  • Binding Specificity
    • full length
    • AA 1-112
    • AA 1-113
  • Conjugate
    • Un-conjugated
    • His-SUMO Tag
    • His tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid

Vpx Protein (VPX) Protein Profile

Protein Summary

Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity). {ECO:0000250}.

Gene names and symbols associated with Vpx Protein Proteins (VPX)

  • vpx protein (vpx) antibody

Protein level used designations for Vpx Protein Proteins (VPX)

Viral protein X , X ORF protein

GENE ID SPECIES
1490006 Simian immunodeficiency virus

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