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ZNF165 encodes a member of the Kruppel family of zinc finger proteins. Additionally we are shipping ZNF165 Antibodies (48) and many more products for this protein.
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ZNF165 drives the unrestrained activation of transforming growth factor beta (TGFbeta (show TGFB1 Proteins)) signalling by directly inactivating the expression of negative feedback pathway regulators, SMURF2 (show SMURF2 Proteins), SMAD7 (show SMAD7 Proteins) and PMEPA1 (show PMEPA1 Proteins).
ZNF165 mRNA/protein expression was observed in TCC (show SFXN1 Proteins) of human urinary bladder and might be used as a novel diagnostic biomarker and as well a vaccine target in development of urinary bladder cancer specific immunotherapy.
This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis.
cancer/testis antigen 53
, zinc finger and SCAN domain-containing protein 7
, zinc finger protein 165
, zinc finger and SCAN domain containing 16