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Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. Additionally we are shipping and many more products for this protein.
Showing 10 out of 144 products:
Cow (Bovine) Monoclonal CLTC Primary Antibody for ICC, FACS - ABIN152766
Fernandez, McVicker, Tuma, Tuma: Ethanol selectively impairs clathrin-mediated internalization in polarized hepatic cells. in Biochemical pharmacology 2009
Show all 6 Pubmed References
Cow (Bovine) Monoclonal CLTC Primary Antibody for WB - ABIN265878
Grossman, Ebke, Beight, Jang, Crabb, Hagstrom: Protein partners of dynamin-1 in the retina. in Visual neuroscience 2013
Human Polyclonal CLTC Primary Antibody for IF (p) - ABIN891159
Kuhn, Vanhecke, Michen, Blank, Gehr, Petri-Fink, Rothen-Rutishauser: Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages. in Beilstein journal of nanotechnology 2014
The clathrin heavy chain CHC-1 negatively regulates pulling forces acting on centrosomes during interphase and on spindle poles during mitosis in one-cell C. elegans embryos.
Inactivating epn-1 (show EPN1 Antibodies) or chc-1 disrupts engulfment by impairing actin polymerization. CHC-1 is enriched on extending pseudopods together with EPN-1 (show EPN1 Antibodies), in an EPN-1 (show EPN1 Antibodies)-dependent manner.
These results indicate that a high level of CHC activity is required for receptor-mediated endocytosis in nonneuronal cells but is largely dispensable for maintenance of synaptic vesicle pools.
Loss of SNX-1 (show SNX1 Antibodies), RME-8, or the clathrin chaperone Hsc70 (show HSPA8 Antibodies)/HSP-1 leads to over-accumulation of endosomal clathrin, reduced clathrin dynamics, and missorting of MIG-14 (show RAE1 Antibodies) to the lysosome.
Taken together, these results demonstrate that Japanese encephalitis virus enters porcine kidney epithelial PK15 cells through cholesterol- and clathrin-mediated endocytosis.
Clathrin plays a crucial role in meiotic spindle function in maturing oocytes, possibly through spindle stabilization
this study shows that clathrin, including the clathrin population associated to internal vesicles, controls lymphocyte migration by regulating actin rearrangements occurring at the leading age
The novel association of several endocytosis-associated proteins has been demonstrated, in particular, of CLTC and SCAMP3 (show SCAMP3 Antibodies) with hepatocellular carcinoma progression.
MiR (show MLXIP Antibodies)-199a-5p suppresses tumorigenesis by targeting CLTC in hepatocellular carcinoma.
Data indicate that clathrin-mediated endocytosis of proto-oncogene (show RAB1A Antibodies) protein erbB-3 (ErbB3 (show ERBB3 Antibodies)) is depending on epsin-1 (show EPN1 Antibodies).
SMAP2 (show BRD8 Antibodies) immunoprecipitated clathrin and AP-1 (show FOSB Antibodies) through a putative clathrin-binding domain and a CALM-binding domain, and SMAP2 (show BRD8 Antibodies) mutants that did not interact with clathrin or AP-1 (show FOSB Antibodies) could not localize to recycling endosomes
autophagy contributed to Cx31.1 (show GJB5 Antibodies) degradation, and clathrin might be involved in the autophagy of Cx31.1 (show GJB5 Antibodies).
Data suggest that by binding to both clathrin and F-actin, mammalian actin-binding protein 1 (mAbp1 (show DBNL Antibodies); HIP-55 (show DBNL Antibodies) or SH3P7 (show DBNL Antibodies)) is specifically recruited at a late stage of clathrin-coated pits (CCPs) formation, which subsequently recruits dynamin (show DNM1 Antibodies) to CCPs.
In conclusion these data suggest that Streptococcus pneumoniae PspC-promoted uptake via the polymeric immunoglobulin receptor of epithelial cells is mediated by both clathrin and caveolin dependent pathway.
Our data support a model in which nascent Hepatits C Virus particles associate with apoE in the endoplasmic reticulum and exit cells following a clathrin-dependent transendosomal secretory route.
clathrin-mediated and caveolae-mediated endocytosis of VE-cad (show CDH5 Antibodies) contribute to lipopolysaccharide-induced vascular hyperpermeability.
three different clathrin-box motif peptides can each simultaneously bind not only to the previously characterized clathrin-box site but also to the W-box site and the beta-arrestin splice loop site on a single TD.
Structure of clathrin coat with bound Hsc70 (show HSPA8 Antibodies) and auxilin (show DNAJC6 Antibodies).
clathrin-FKBP36-Hsp72 complexes resulting from both identified interactions are bound to the matrices of clathrin-coated vesicles in spermatocytes, which indicates a possible role of FKBP36 and Hsp72 in the disassembly of clathrin coats
our results demonstrate that CKAP5 (show CKAP5 Antibodies) is important in oocyte maturation and early embryo development, and CKAP5 (show CKAP5 Antibodies) might work together with CLTC in mouse oocyte maturation
SP-A (show SFTPA1 Antibodies) transiently enhances the basal protein expression of CHC and alpha-adaptin (show AP2A2 Antibodies).
PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.
The clathrin-mediated endocytic machinery combines with Dab2 (show DAB2 Antibodies) to facilitate the endocytosis of RGD-integrin-beta3 clusters.
Taken together, these results show that CLTC plays an important role in spindle assembly and chromosome congression through a microtubule correlation mechanism during mouse oocyte maturation.
Auditory inner hair cells use dynamin-dependent endocytosis via clathrin-mediated endocytosis.
Data indicate that dynamin (show DNM1 Antibodies), clathrin, adaptor protein complex-2 (AP2 (show TFAP2A Antibodies)), and amphiphysin (show AMPH Antibodies) contribute to the depolarization-evoked entry in endocytosis.
This study reveals a novel functional role of clathrin-coated structure in GMR (show CSF2RA Antibodies) signaling and the oncogenesis of JAK2V617F.
The authors report that Dab2, previously described as an inhibitor of Wnt/beta-catenin signalling, selectively recruits LRP6 to the clathrin-dependent endocytic route, thereby sequestering it from caveolin-mediated endocytosis.
Data indicate that MTV1 (AT3G16270) and AGD5 (AT5G54310) Physically Interact with clathrin.
study presents a genetic characterization of the role of clathrin in endocytosis and auxin-mediated plant development; data demonstrate a fundamental role for clathrin function in cell polarity, growth, patterning, and organogenesis
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.
clathrin heavy chain
, Clathrin Heavy Chain family member (chc-1)
, clathrin heavy chain 1
, clathrin heavy-chain
, clathrin, heavy polypeptide (Hc)
, clathrin heavy chain on chromosome 17
, clathrin, heavy polypeptide-like 2
, clathrin, heavy chain (Hc)
, clathrin, heavy chain (Hc) L homeolog