Clathrin Heavy Chain (CLTC) (AA 851-990) antibody

Catalog No. ABIN7147846

Product Details

Target: Clathrin Heavy Chain (CLTC)

Binding Specificity: AA 851-990

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Clathrin heavy chain 1 protein (851-990aa)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Clathrin Heavy Chain (CLTC)

Alternative Name: CLTC (CLTC Products)

Synonyms: CHC antibody, Chc antibody, CHC17 antibody, CLH-17 antibody, CLTCL2 antibody, Hc antibody, CLTC antibody, 3110065L21Rik antibody, R74732 antibody, F11B9.30 antibody, cb1033 antibody, cltc antibody, wu:fc03e11 antibody, wu:fc49a11 antibody, wu:fd07f02 antibody, clathrin heavy chain antibody, Probable clathrin heavy chain 1 antibody, putative clathrin heavy chain antibody, clathrin heavy chain 1 antibody, clathrin heavy chain Chc1 antibody, clathrin, heavy polypeptide (Hc) antibody, Clathrin, heavy chain antibody, clathrin, heavy chain a (Hc) antibody, clathrin, heavy chain (Hc) L homeolog antibody, CHC1 antibody, chc-1 antibody, CLTC antibody, Chc antibody, TP03_0480 antibody, LOC5578293 antibody, LMJF_36_1630 antibody, CpipJ_CPIJ014882 antibody, CNJ03270 antibody, ATEG_05434 antibody, CMU_025200 antibody, PMAA_094250 antibody, SJAG_02282 antibody, Smp_154420.1 antibody, PAAG_00730 antibody, MCYG_06136 antibody, VDBG_05048 antibody, MGYG_04658 antibody, cgd8_1270 antibody, Tc00.1047053506167.50 antibody, CHC antibody, Cltc antibody, AT3G11130 antibody, cltca antibody, cltc.L antibody

Background:

Background: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577, PubMed:16968737, PubMed:21297582). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Plays a role in early autophagosome formation (PubMed:20639872).

Aliases: Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17), CLTC, CLH17 CLTCL2 KIAA0034

UniProt: Q00610