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The protein encoded by SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, developmen. Additionally we are shipping serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 Proteins (7) and many more products for this protein.
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Human Polyclonal SERPINI2 Primary Antibody for IHC, ELISA - ABIN185374
Ozaki, Nagata, Suzuki, Fujiwara, Miyoshi, Ishikawa, Ohigashi, Imaoka, Takahashi, Nakamura: Isolation and characterization of a novel human pancreas-specific gene, pancpin, that is down-regulated in pancreatic cancer cells. in Genes, chromosomes & cancer 1998
Show all 3 Pubmed References
The rescue of growth retardation, immunodeficiency, and mortality by either Serpini2 bacterial artificial chromosome transgenic expression or by pancreatic enzyme supplementation demonstrates these phenotypes as secondary to malnutrition.
The findings indicate that SERPINI2 is a promising candidate for further investigations of the genetic susceptibility to myopia.
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene.
serpin peptidase inhibitor, clade I (pancpin), member 2
, serpin I2
, serpin I2-like
, pancreas-specific serpin
, serine protease inhibitor 14
, myoepithelium-derived serine protease inhibitor
, pancreas-specific protein TSA2004
, peptidase inhibitor 14
, protease inhibitor 14
, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2
, serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2
, serine (or cysteine) peptidase inhibitor, clade I, member 2
, serpin peptidase inhibitor, clade I, member 2