Valinomycin

Catalog No. ABIN1027805

Product Details

Purpose: Apoptosis Inducer

Characteristics: Induces loss of mitochondrial membrane potential.

Purity: >98 %

Chemical Name: (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone

Formula: C54H90N6O18

Solubility: Soluble to 25 mM in DMSO and 25 mM in ethanol.

Application Details

Comment:

Source: Synthetic.
Appearance: White Solid

Restrictions: For Research Use only

Handling

Format: Solid

Precaution of Use: Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H300-H310 Precautionary Phrases: P264-P280-P302 + P350-P310

Handling Advice: Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed R68 - Possible risk of irreversible effects Hazard Phrases: H300-H310 Precautionary Phrases: P264-P280-P302 + P350-P310

Storage: -20 °C

Target Details

Background: Valinomycin is a dodecadepsipeptide, and a member of a group of natural neutral ionophores. It is highly selective for potassium ions within the cell membrane. It functions as a potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes down an electrochemical potential gradient.

Molecular Weight: 1111.32

CAS-No: 2001-95-8