anti-CMA1 Antibodies

Protein Summary

This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.

Alternative names and synonyms associated with CMA1

• chymase 1 (CMA1) antibody
• chymase 1 (Cma1) antibody
• chymase 1, mast cell (CMA1) antibody
• chymase 1, mast cell (Cma1) antibody
• chymase-like (LOC100008644) antibody

• Chymase antibody
• CMA1 antibody
• CYH antibody
• Mcp-5 antibody
• MCP3P antibody
• Show all synonym aliases
• Mcp5 antibody
• Mcpt5 antibody
• MCT1 antibody
• MMCP-5 antibody

Protein level used designations for CMA1

alpha-chymase , chymase , chymase 1 preproprotein transcript E , chymase 1 preproprotein transcript I , chymase, heart , chymase, mast cell , mast cell protease I , mast cell chymase , serine protease , SMCP-2 , mast cell protease 2 , mast cell chymase 1 , mast cell protease 5 , mast cell protease 3 , mast cell protease III , rMCP-3 , rMCP-5 , rMCP-III , chymase 1, mast cell , Alpha-chymase , LOW QUALITY PROTEIN: chymase , chymase like protein , preprochymase