Browse our anti-ADAM8 (ADAM8) Antibodies

Full name:: anti-ADAM Metallopeptidase Domain 8 Antibodies (ADAM8)

On www.antibodies-online.com are 121 ADAM Metallopeptidase Domain 8 (ADAM8) Antibodies from 22 different suppliers available. Additionally we are shipping ADAM8 Kits (49) and ADAM8 Proteins (13) and many more products for this protein. A total of 190 ADAM8 products are currently listed.

Synonyms:: ADAM8, CD156, CD156a, E430039A18Rik, MS2, reprolysin, RGD1566394, si:zc217g15.7, zgc:64059

list all antibodies	Gene Name	GeneID	UniProt
	ADAM8	101	P78325
	ADAM8	11501	Q05910
	ADAM8	499285
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Top referenced anti-ADAM8 Antibodies

Human Polyclonal ADAM8 Primary Antibody for WB - ABIN611315 : Barbara, Wrana, Letarte: Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. in The Journal of biological chemistry 1999 (PubMed)
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Human Monoclonal ADAM8 Primary Antibody for CyTOF, FACS - ABIN4899269 : Johansson, Lye, Barthel, Duffy, Annis, Mosher: Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes. in American journal of respiratory cell and molecular biology 2004 (PubMed)
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Human Polyclonal ADAM8 Primary Antibody for ELISA, WB - ABIN249497 : Yoshiyama, Higuchi, Kataoka, Matsuura, Yamamoto: CD156 (human ADAM8): expression, primary amino acid sequence, and gene location. in Genomics 1997 (PubMed)

More Antibodies against ADAM8 Interaction Partners

Human ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

Authors conclude that ADAM8 promotes early metastatic processes such as transendothelial migration by upregulation of MMP-9 (show MMP9 Antibodies) and shedding of PSGL-1 (show SELPLG Antibodies) from breast cancer cells.
ADAM8 on leukocytes holds a proinflammatory function in acute lung inflammation by promoting alveolar leukocyte recruitment.
miR (show MLXIP Antibodies)-720 is elevated in serum of patients with ADAM8-high TNBC and, in a group with other miRNAs downstream of ADAM8, holds promise as a biomarker for early detection of or treatment response of ADAM8-positive triple-negative breast cancer
ADAM8 causes temozolomide resistance in glioblastoma cells by enhancing pAkt/PI3K, pERK1/2, and cleavage of CD44 and HGF R/c-met
ADAM8 promotes GC cell proliferation and invasion, and its expression is positively correlated with poor survival, indicating that it might be a promising target in GC therapy
ADAM8 expression is associated with increased migration and invasiveness of pancreatic ductal adenocarcinoma cells.
ADAM8 and endostatin (show COL18A1 Antibodies) play a role in osteosarcoma progression.
Data indicate that fibronectin fragments (FN-fs) are present in adult ntervertebral disc (IVD) from adult subjects, and ADAM-8, known to cleave FN, is present at the pericellular matrix of disc cells.
Results show that ADAM8 is overexpressed in colorectal cancer and promotes cell growth.
N-glycosylation is essential for processing, localization, stability, and activity of ADAM8.

Mouse (Murine) ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

ADAM8 on leukocytes holds a proinflammatory function in acute lung inflammation by promoting alveolar leukocyte recruitment.
The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice
ADAM8 mediates an enhanced invasiveness of neutrophils into injured muscle fibers by the removal of their adhesiveness to blood vessels after infiltration into interstitial tissues.
ADAM8 has anti-inflammatory activities during allergic airway inflammation in mice
overexpression of PrP(C (show PRNP Antibodies)) led to up-regulation of ADAM8, suggesting that PrP(C (show PRNP Antibodies)) may regulate its own alpha-cleavage through modulating ADAM8 activity.
ADAM-8 appears to favour allergen-induced acute airway inflammation by promoting dendritic cell recruitment and CCL11 and CCL22 (show CCL22 Antibodies) production.
ADAM8 knockout mice did not display a bone phenotype in vivo but they did not increase RANKL (show TNFSF11 Antibodies) production, OCL (show OCLN Antibodies) formation, or calvarial fibrosis in response to tumor necrosis factor alpha (TNF-alpha (show TNF Antibodies)) in vivo.
ADAM8 is involved in T cell maturation in the medulla but has a relatively minor impact on T cell development.
The results of this study indicated an essential role for ADAM8 in modulating TNF-alpha (show TNF Antibodies) signaling in CNS diseases
The study finds an increase in retinal re-vascularization but fewer neovascular tufts in the oxygen-induced retinopathy model and increased growth of heterotopically injected tumor cells in Adam8-/- mice compared with wild-type controls.

ADAM8 Antigen Profile

Antigen Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with ADAM8

ADAM metallopeptidase domain 8 (ADAM8) antibody
a disintegrin and metalloproteinase domain 8 (LOC100304737) antibody
a disintegrin and metallopeptidase domain 8 (Adam8) antibody
ADAM metallopeptidase domain 8a (adam8a) antibody
ADAM metallopeptidase domain 8 (Adam8) antibody
a disintegrin and metalloproteinase domain 8 (adam8) antibody

ADAM8 antibody
CD156 antibody
CD156a antibody
E430039A18Rik antibody
MS2 antibody
reprolysin antibody
RGD1566394 antibody
si:zc217g15.7 antibody
zgc:64059 antibody

Protein level used designations for ADAM8

a disintegrin and metalloproteinase domain 8 , cell surface antigen MS2 , disintegrin and metalloproteinase domain-containing protein 8 , human leukocyte differentiation antigen , ADAM 8 , a disintegrin and metalloprotease domain (ADAM) 8 , a disintegrin and metalloprotease domain 8 , macrophage cysteine-rich glycoprotein , CD156a , metalloprotease , ADAM metallopeptidase domain 8 , a disintegrin and metallopeptidase domain 8 , disintegrin and metalloproteinase domain-containing protein 8-like

GENE ID	SPECIES
101	Homo sapiens
100304737	Ictalurus punctatus
11501	Mus musculus
368917	Danio rerio
423672	Gallus gallus
491699	Canis lupus familiaris
499285	Rattus norvegicus
519652	Bos taurus
100156146	Sus scrofa
100303713	Ictalurus punctatus
100393217	Callithrix jacchus
100428452	Macaca mulatta
100471554	Ailuropoda melanoleuca
100726804	Cavia porcellus

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Show all anti-ADAM Metallopeptidase Domain 8 (ADAM8) Antibodies with Pubmed References

Human ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

Mouse (Murine) ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

Antigen Summary

Alternative names and synonyms associated with ADAM8

Protein level used designations for ADAM8