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anti-Human Cathepsin S Antibodies:
anti-Mouse (Murine) Cathepsin S Antibodies:
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Human Polyclonal Cathepsin S Primary Antibody for IP, IHC - ABIN223091
Zaehringer, Sapoval, Pattynama, Rabbia, Vignali, Maleux, Boyer, Szczerbo-Trojanowska, Jaschke, Hafsahl, Downes, Beregi, Veeger, Stoll, Talen: Sirolimus-eluting versus bare-metal low-profile stent for renal artery treatment (GREAT Trial): angiographic follow-up after 6 months and clinical outcome up to 2 years. in Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 2007
Show all 4 Pubmed References
Human Polyclonal Cathepsin S Primary Antibody for ICC, IF - ABIN4288275
Ma, Visser, Roelofsen, de Vries, Diepstra, van Imhoff, van der Wal, Luinge, Alvarez-Llamas, Vos, Poppema, Vonk, van den Berg: Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes. in Blood 2008
Show all 2 Pubmed References
Human Polyclonal Cathepsin S Primary Antibody for IHC, IHC (fro) - ABIN4288274
Otsuki, Sawada, Yodoya, Shinohara, Kato, Ohashi, Zhang, Imanaka-Yoshida, Shimpo, Maruyama, Komada, Mitani: Potential contribution of phenotypically modulated smooth muscle cells and related inflammation in the development of experimental obstructive pulmonary vasculopathy in rats. in PLoS ONE 2015
This study suggested serum Cat S may be a potential biomarker for the diagnosis and prognosis of gastric cancer
Overall, these results indicate that exploitation of the cathepsin S activity in MPS tissues can be utilized to substantially lower non-target accumulation, suggesting this is a promising approach for the development of diagnostic and radiotherapeutic nanomedicine platforms.
polymorphism of rs7534124 and rs1136774 in cathepsin S promoter may decrease the susceptibility of asthma in a Chinese Han population
cathepsin S mRNA (CTSS), which encodes a cysteine protease (show CTSB Antibodies) associated with angiogenesis and atherosclerosis, is highly edited in human endothelial cells. RNA editing enables the recruitment of the stabilizing RNA-binding protein (show PTBP1 Antibodies) human antigen R (HuR (show ELAVL1 Antibodies); encoded by ELAVL1 (show ELAVL1 Antibodies)) to the 3' UTR (show UTS2R Antibodies) of the CTSS transcript, thereby controlling CTSS mRNA stability and expression.
levels of cathepsin S and hsCRP observed in women who later developed breast cancer may provide prognostic information regarding tumor development and need to be evaluated in prospective studies.
p41 (show EPB41 Antibodies) fragment is also shown to reduce the secretion of interleukin-12 (IL-12 (show IL12A Antibodies)/p70 (show ANXA6 Antibodies)) during the subsequent maturation of treated dendritic cells.
shedding of surface proteins by extracellular cathepsins impacts intracellular signaling as demonstrated for regulation of Ras GTPase (show RACGAP1 Antibodies) activity.
the essential role of autophagy-regulated early ROS (show ROS1 Antibodies) in triggering late apoptotic signaling
Cathepsin S cleaves near the N-terminus of PAR2 (show F2RL1 Antibodies) to expose a novel tethered ligand, KVDGTS.
Increased plasma CTSS concentration is associated with atherogenesis.
the roles of CTSB (show CTSB Antibodies)/S and SIRT1 (show SIRT1 Antibodies) in the regulation of hepatic inflammation using primary parenchymal and non-parenchymal hepatic cell types and cell lines.
Cathepsin S activity controls injury-related vascular remodeling via TLR2 (show TLR2 Antibodies)/p38MAPK (show MAPK14 Antibodies)/PI3K/Akt (show AKT1 Antibodies)/p-HDAC6 (show HDAC6 Antibodies) signaling pathway.
Loss of Rab3D (show RAB3D Antibodies) from secretory vesicles, leading to disproportionate Rab27 (show RAB27A Antibodies)-to-Rab3D (show RAB3D Antibodies) activity, may contribute to the enhanced release of cathepsin S in tears of patients with Sjogren's syndrome.
Ctss induction during muscular dystrophy is a pathologic event that partially underlies disease pathogenesis, and its inhibition might serve as a new therapeutic strategy in Duchenne muscular dystrophy (show DMD Antibodies).
Demonstrate the utility of intracellular caspase 1 (show CASP1 Antibodies) and extracellular CTSS proteolytic activities as surrogate biomarkers of lysosomal rupture and acute inflammation.
Fluorogen substrate, Mca (show RSPH1 Antibodies)-GRWPPMGLPWE-Lys (show LYZ Antibodies)(Dnp)-DArg-NH2 can detect CTSS activities in mouse antigen presenting cells.
Data show that cathepsins S (CatS) regulates CCL2 (show CCL2 Antibodies) chemokine (show CCL1 Antibodies) expression by modulation of CD74 (show CD74 Antibodies) antigen processing.
Cathepsin S activates MrgprC11 (show MRGPRX1 Antibodies) and evokes receptor-dependent scratching in mice.
cathepsin S deficiency alters the balance between adipocyte and osteoblast differentiation, increases bone turnover, and changes bone microarchitecture. Therefore, bone and fat metabolisms should be monitored when using cathepsin S inhibitors clinically
results identify Cat-S as a biased agonist of PAR2 (show F2RL1 Antibodies) that causes PAR2 (show F2RL1 Antibodies)- and TRPV4 (show TRPV4 Antibodies)-dependent inflammation and pain.
The cathepsin S deserves further evaluation as therapeutic targets to develop disease modifying drugs to treat Alzheimer's disease.
These results, together with those previously reported for other genes of this family, suggest that cathepsin genes play a role in defining economically important traits in pigs.
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
, cathepsin S
, cathepsin S, gene 1
, Cathepsin S