Browse our anti-IFI16 (IFI16) Antibodies

Full name:: anti-Interferon, gamma-Inducible Protein 16 Antibodies (IFI16)

On www.antibodies-online.com are 87 Interferon, gamma-Inducible Protein 16 (IFI16) Antibodies from 19 different suppliers available. Additionally we are shipping IFI16 Kits (27) and IFI16 Proteins (7) and many more products for this protein. A total of 128 IFI16 products are currently listed.

Synonyms:: IFI16, Ifitm3l, Ifitml, IFNGIP1, p204, PYHIN2

list all antibodies	Gene Name	GeneID	UniProt
	IFI16	3428	Q16666
	IFI16	15951	P15092 , Q08619
	IFI16	114709
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Top referenced anti-IFI16 Antibodies

Human Monoclonal IFI16 Primary Antibody for IHC (p), ELISA - ABIN516822 : Anthonio, Brees, Baumgart-Vogt, Hongu, Huybrechts, Van Dijck, Mannaerts, Kanaho, Van Veldhoven, Fransen: Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6. in BMC cell biology 2009 (PubMed)
Human Polyclonal IFI16 Primary Antibody for ICC, IF - ABIN4321056 : Tervaniemi, Katayama, Skoog, Siitonen, Vuola, Nuutila, Sormunen, Johnsson, Linnarsson, Suomela, Kankuri, Kere, Elomaa: NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis. in Scientific reports 2016 (PubMed)

More Antibodies against IFI16 Interaction Partners

Human Interferon, gamma-Inducible Protein 16 (IFI16) interaction partners

This study found IFI16 and AIM2 (show AIM2 Antibodies) SNPs associated with higher levels of periodontal microorganisms and an increased percentage of periodontal disease clinical parameters.
Importantly, knocking down p204, which is reported as the mouse orthologous of human IFI16, inhibited epidermal hyperplasia in mice with imiquimod-induced psoriasiform dermatitis. These findings indicate that IFI16 plays a critical role in the pathogenesis of psoriasis and may be a potential therapeutic target
IFI16 is a tumour suppressor in HCC (show FAM126A Antibodies) via activation of p53 (show TP53 Antibodies) signals and inflammasome
in a cohort of patients with genital herpes and healthy controls, the minor G allele of the IFI16 single nucleotide polymorphism rs2276404 was associated with resistance to infection
study identifies the AIM2 (show AIM2 Antibodies) inflammasome and cGAS/IFI16-STING-type I IFN pathway as a novel mechanism for host innate immunity to the ALVAC vaccine vector.
this study shows that IFI16 is not essential for the IFN response to human cytomegalovirus infection
findings show that IFI16 rapidly oligomerizes at incoming herpesvirus genomes at the nuclear periphery to transcriptionally repress viral gene expression and limit viral replicative capacity; further demonstrate that IFI16 does not initiate upstream activation of the canonical STING/TBK-1 (show TBK1 Antibodies)/IRF3 (show IRF3 Antibodies) signaling pathway but is required for downstream antiviral cytokine expression.
The authors observed that a reduced IFI16 expression was associated with a very poor survival in chronic lymphocytic leukemia, but only in cases with ZAP70/CD38 expression.
Findings indicate that expression of the scleroderma autoantigens IFI-16 and CENPs (show APITD1 Antibodies), which are associated with severe vascular disease, is increased in vascular progenitors and mature endothelial cells. High level, lineage-enriched expression of autoantigens may explain the striking association between clinical phenotypes and the immune targeting of specific autoantigens.
DDR (show DDR1 Antibodies)-induced signaling in cells activates the ATM (show ATM Antibodies)-p53 (show TP53 Antibodies) and ATM (show ATM Antibodies)-IKKalpha (show CHUK Antibodies)/beta-interferon (show IFNA Antibodies) (IFN)-beta (show IFNB1 Antibodies) signaling pathways, thus leading to an induction of the p53 (show TP53 Antibodies) and IFN-inducible IFI16 gene

Mouse (Murine) Interferon, gamma-Inducible Protein 16 (IFI16) interaction partners

Importantly, knocking down p204, which is reported as the mouse orthologous of human IFI16, inhibited epidermal hyperplasia in mice with imiquimod-induced psoriasiform dermatitis. These findings indicate that IFI16 plays a critical role in the pathogenesis of psoriasis and may be a potential therapeutic target
Ifi204 is required for EPC (show TCF21 Antibodies) differentiation.
study identifies the AIM2 (show AIM2 Antibodies) inflammasome and cGAS/IFI16-STING-type I IFN pathway as a novel mechanism for host innate immunity to the ALVAC vaccine vector.
p204 initiated innate antiviral responses in adipose cells, thereby modulating adipocyte function.
cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection.
The present study demonstrated that mouse Leydig cells had innate antiviral activities in response to viral DNA challenge through p204 activation.
Data indicate that the transient expression of p204 in the early stage is indispensable for adipocyte differentiation. Disruption of p204 expression patterns at this stage leads to irreversible damage in fat formation.
IFI16 exerts in vivo anti-tumoral activity by promoting apoptosis of tumor cells.
This gene product interacts with the Tpr protein, a component of the nuclear pore complex.
expression of p204 is activated by the cardiac Gata4 (show GATA4 Antibodies), Nkx2.5 (show NKX2-5 Antibodies), and Tbx5 (show TBX5 Antibodies) proteins

IFI16 Antigen Profile

Antigen Summary

This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IFI16

interferon gamma inducible protein 16 (IFI16) antibody
interferon activated gene 204 (Ifi204) antibody
interferon induced transmembrane protein 2 (Ifitm2) antibody
myeloid cell nuclear differentiation antigen-like protein (LOC100156073) antibody
interferon-activable protein 203 (LOC488622) antibody
interferon gamma inducible protein 16 (Ifi16) antibody

IFI16 antibody
Ifitm3l antibody
Ifitml antibody
IFNGIP1 antibody
p204 antibody
PYHIN2 antibody

Protein level used designations for IFI16

gamma-interferon-inducible protein 16 , interferon-gamma induced protein IFI 16 , interferon-inducible myeloid differentiation transcriptional activator , ifi-204 , interferon, gamma-inducible gene 204 , interferon, gamma-inducible protein 16 , interferon-activable protein 204 , interferon-inducible protein p204 , Gamma-interferon-inducible protein Ifi-16 , ifi-16 , interferon induced transmembrane protein 2 (1-8D) , interferon induced transmembrane protein, like , interferon-induced transmembrane protein 2 , interferon-inducible protein 16 , interferon activated gene 203 , interferon-activable protein 203 , pyrin and HIN domain-containing protein 1

GENE ID	SPECIES
3428	Homo sapiens
15951	Mus musculus
457424	Pan troglodytes
506759	Bos taurus
100172051	Pongo abelii
100607897	Nomascus leucogenys
114709	Rattus norvegicus
100156073	Sus scrofa
488622	Canis lupus familiaris
100717636	Cavia porcellus
101112936	Ovis aries musimon

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Show all anti-Interferon, gamma-Inducible Protein 16 (IFI16) Antibodies with Pubmed References

Human Interferon, gamma-Inducible Protein 16 (IFI16) interaction partners

Mouse (Murine) Interferon, gamma-Inducible Protein 16 (IFI16) interaction partners

Antigen Summary

Alternative names and synonyms associated with IFI16

Protein level used designations for IFI16