ITCH ELISA Kits

Protein Summary

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with ITCH

• itchy E3 ubiquitin protein ligase (ITCH) antibody
• itchy, E3 ubiquitin protein ligase (Itch) antibody
• itchy E3 ubiquitin protein ligase (Itch) antibody

• 6720481N21Rik antibody
• 8030492O04Rik antibody
• A130065M08 antibody
• AIF4 antibody
• AIP4 antibody
• Show all synonym aliases
• C230047C07Rik antibody
• dJ468O1.1 antibody
• NAPP1 antibody

Protein level used designations for ITCH

E3 ubiquitin-protein ligase Itchy homolog , NFE2-associated polypeptide 1 , atrophin-1 interacting protein 4 , dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4)) , itchy E3 ubiquitin protein ligase homolog , E3 ubiquitin-protein ligase Itchy , itch E3 ubiquitin ligase , itchy homolog E3 ubiquitin protein ligase