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Browse our anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) Antibodies

Full name:: anti-Ubiquitin-Conjugating Enzyme E2D 1 Antibodies (UBE2D1)

On www.antibodies-online.com are 76 Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) Antibodies from 22 different suppliers available. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2D 1 Proteins (16) and and many more products for this protein. A total of 96 Ubiquitin-Conjugating Enzyme E2D 1 products are currently listed.

Synonyms:: e2(17)kb1, sft, ubc4/5, ubch5, ubch5a, ube2d1, wu:fc16h06, zgc:73096

list all antibodies	Gene Name	GeneID	UniProt
	UBE2D1	7321	P51668
	UBE2D1	216080	P61080
	UBE2D1	361831	D3ZDK2
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Most Popular Reactivities for anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) Antibodies

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Top referenced anti-Ubiquitin-Conjugating Enzyme E2D 1 Antibodies

Human Polyclonal UBE2D1 Primary Antibody for IHC (p), ELISA - ABIN544849 : Brès, Kiernan, Linares, Chable-Bessia, Plechakova, Tréand, Emiliani, Peloponese, Jeang, Coux, Scheffner, Benkirane: A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter. in Nature cell biology 2003 (PubMed)
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Human Monoclonal UBE2D1 Primary Antibody for IHC (p), ELISA - ABIN521211 : Zhu, Du, Zhou, Roizman: The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase. in Journal of virology 2014 (PubMed)
Human Polyclonal UBE2D1 Primary Antibody for ELISA, WB - ABIN563315 : Basic, Tadele, Elmabsout, Yao, Rahman, Sirsjö, Abdel-Halim: Exposure to cigarette smoke induces overexpression of von Hippel-Lindau tumor suppressor in mouse skeletal muscle. in American journal of physiology. Lung cellular and molecular physiology 2012 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2D 1 Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) interaction partners

Results showed that although UBE2D1 RNA was significantly upregulated in both lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) tissues; its expression was even higher in LUAD tissues than in LUSC. UBE2D1 RNA upregulation was associated with poor survival in LUAD patients, but not in LUSC suggesting it as an independent indicator of unfavorable prognosis in LUAD, but not in LUSC.
Upregulation of UBE2D1 promoted HCC growth in vitro and in vivo by decreasing the p53 in ubiquitination-dependent pathway. High expression of UBE2D1 was attributed to the recurrent genomic copy number gain, which was associated with high serum IL-6 level of HCC patients.
March-I undergoes lysine-independent ubiquitination by an as yet unidentified E3 ubiquitin ligase that, together with Ube2D1, regulates March-I expression
The anaphase-promoting complex/cyclosome C activity in human cells is tuned by the combinatorial use of three E2 ubiquitin-conjugating enzymes, namely UBE2C, UBE2S, and UBE2D.
Data show that ubiquitin E2 enzymes UBE2D1/2/3 and E3 ligase RNF138 accumulate at DNA-damage sites and act at early resection stages by promoting CtIP protein ubiquitylation and accrual.
The Asp17 mutation in MDM2 stimulated its discharge of the UBCH5a-ubiquitin thioester adduct.
The SMURF2:UBCH5 complex is critical in maintaining KRAS protein stability.
Biochemical characterization of recombinant UBTD1 and UBE2D demonstrated that the two proteins form a stable, stoichiometric complex that can be purified to near homogeneity.
crystal structure of the dimeric RING domain of rat RNF4 in complex with E2 (UbcH5A) linked by an isopeptide bond to ubiquitin
These data demonstrate that the ability of ICP0 to interact with cellular E2 ubiquitin-conjugating enzyme UBE2D1 is fundamentally important for its biological functions during HSV-1 infection.
identify the IDOL-UBE2D complex as an important determinant of LDLR activity, and provide insight into molecular mechanisms underlying the regulation of cholesterol uptake
This structure reveals an interaction between the ubiquitin surface flanking K11 and residues adjacent to the E2 catalytic cysteine and suggests a possible role for this surface in formation of K11 linkages.
The authors demonstrate that c-IAP1 and UbcH5 family promote K11-linked polyubiquitination of receptor-interacting protein 1 (RIP1) in vitro and in vivo.
Whereas UbcH5(A, B and C) is highly efficient in converting IkBa into monoubiquitinated forms, Cdc34 drives ubiquitin (Ub)-Ub conjugation
conformational changes in CHIP upon binding of Hsp70, Hsp90, and their respective C-terminal EEVD peptides, and in complex with the different E2 ubiquitin-conjugating enzymes UbcH5a and Ubc13
UbcH5A is up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, but in vitro studies failed to show regulation in response to iron loading or chelation. Earlier in vivo mRNA expression data for SFT might be UbcH5A.
comparison of the regional distribution of SFT/UbcH5A and DMT1 mRNA in the adult brain
Ro52 has both cytoplasmic and nuclear substrates, and mediates ubiquitination through UBE2D1 in the cytoplasm and through UBE2E1 in the nucleus.
Catalytically active Ubc5 is required for IRF3 activation by viral infection.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) interaction partners

Its gene expression is inhibited through p53 dependent apoptosis, which is induced by cadmium exposure.(review)
significantly elevated levels of SFT/UbcH5A mRNA in the neonatal mouse and its localization to choroid plexus suggest that this factor may contribute to the rapid rate of brain iron uptake that occurs in the early postnatal period

Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) Antigen Profile

Antigen Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1)

ubiquitin conjugating enzyme E2 D1 (UBE2D1) antibody
ubiquitin-conjugating enzyme E2D 1 (Ube2d1) antibody
ubiquitin-conjugating enzyme E2D 1b (ube2d1b) antibody
ubiquitin conjugating enzyme E2 D1 S homeolog (ube2d1.S) antibody
ubiquitin conjugating enzyme E2 D1 (ube2d1) antibody
ubiquitin conjugating enzyme E2 D1 (Ube2d1) antibody

e2(17)kb1 antibody
sft antibody
ubc4/5 antibody
ubch5 antibody
ubch5a antibody
ube2d1 antibody
wu:fc16h06 antibody
zgc:73096 antibody

Protein level used designations for UBE2D1

UBC4/5 homolog , stimulator of Fe transport , ubiquitin carrier protein D1 , ubiquitin-conjugating enzyme E2 D1 , ubiquitin-conjugating enzyme E2(17)KB 1 , ubiquitin-conjugating enzyme E2-17 kDa 1 , ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) , ubiquitin-protein ligase D1 , E2(17)KB 1 , ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog , ubiquitin-conjugating enzyme E2D 1 , ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog)

GENE ID	SPECIES
7321	Homo sapiens
216080	Mus musculus
361831	Rattus norvegicus
324015	Danio rerio
423641	Gallus gallus
495381	Xenopus laevis
535287	Bos taurus
608578	Canis lupus familiaris
701491	Macaca mulatta
745141	Pan troglodytes
780353	Xenopus (Silurana) tropicalis
100355225	Oryctolagus cuniculus
100734273	Cavia porcellus

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Show all anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) Antibodies with Pubmed References

Human Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) interaction partners

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) interaction partners

Antigen Summary

Alternative names and synonyms associated with Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1)

Protein level used designations for UBE2D1