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Browse our anti-Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Antibodies

Full name:: anti-Ubiquitin-Conjugating Enzyme E2D 2 Antibodies (UBE2D2)

On www.antibodies-online.com are 109 Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Antibodies from 22 different suppliers available. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2D 2 Proteins (16) and many more products for this protein. A total of 134 Ubiquitin-Conjugating Enzyme E2D 2 products are currently listed.

Synonyms:: E2(17)KB2, E217kB, PUBC1, Ubc2e, UBC4, UBC4/5, UBCH5B, Ube2d2, zgc:55886

list all antibodies	Gene Name	GeneID	UniProt
	UBE2D2	7322	P62837
	UBE2D2	641452	P62839
	UBE2D2
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Top referenced anti-Ubiquitin-Conjugating Enzyme E2D 2 Antibodies

Human Monoclonal UBE2D2 Primary Antibody for IHC (p), ELISA - ABIN521212 : Peters, Rees, Hardwick, Hardwick, Vowler, Ong, Zhang, Save, ODonovan, Rassl, Alderson, Caldas, Fitzgerald: A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia. in Gastroenterology 2010 (PubMed)
Cow (Bovine) Polyclonal UBE2D2 Primary Antibody for IHC, WB - ABIN2775673 : Desforges, Lacey, Glazier, Greenwood, Mynett, Speake, Sibley: SNAT4 isoform of system A amino acid transporter is expressed in human placenta. in American journal of physiology. Cell physiology 2005 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2D 2 Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

results disclose the mechanism by which cIAP1 RING dimer activates UbcH5B approximately Ub and indicate that noncovalent Ubiquitin (Ub) binding further stabilizes the cIAP1-UbcH5B approximately Ubiquitin (Ub) complex in the active conformation to stimulate Ub transfer
These results point to an important role of the affinity between RNF4 and its cognate RAD6B or UBCH5B in governing the multiplicity of substrate ubiquitination.
Knockdown of UBE2D2 caused an increase in p53 protein levels, and knockdown of p53 attenuated not only cadmium-induced apoptosis, but also cadmium-induced apoptosis-related gene expression.
mutations having marked effects on function only minimally affect the intermolecular interactions between the AO7 RING and UbcH5B, establishing a high degree of complexity in activation through the RING-E2 interface.
Data show that ubiquitin E2 enzymes UBE2D1/2/3 and E3 ligase RNF138 accumulate at DNA-damage sites and act at early resection stages by promoting CtIP protein ubiquitylation and accrual.
together with UBE2L3 and UBE2N, synergistically contribute to Parkin-mediated mitophagy
Presented is the structure of the human dimeric RING domain from BIRC7 in complex with the E2 UbcH5B covalently linked to Ub.
Whereas UbcH5(A, B and C) is highly efficient in converting IkBa into monoubiquitinated forms, Cdc34 drives ubiquitin (Ub)-Ub conjugation
determined the 2.2 A crystal structure of an intermediate of UbcH5b approximately ubiquitin (Ub) conjugate, which is assembled into an infinite spiral through the backside interaction.
role of WW3 and WW4 domains of Nedd4-2 in dopamine transporter ubiquitination was demonstrated; siRNA analysis demonstrated that this polyubiquitination is mediated by Nedd4-2 cooperation with UBE2D and UBE2L3 E2 ubiquitin-conjugating enzymes
Results describe the crystal structure of a complex between the HECT domain of NEDD4L and the E2 UbcH5B bearing a covalently linked Ub at its active site (UbcH5B approximately Ub).
Data show that binding of the CNOT4 RING finger to the ubiquitin-conjugating enzyme (E2) UbcH5B is highly selective.
UbcH5B/C are E2s for Mdm2, which contribute to the maintenance of low levels of p53 and Mdm2 in unstressed cells; inhibition of p53 ubiquitination and degradation by targeting UbcH5B/C is not sufficient to up-regulate p53 transcriptional activity.
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
UBE2D2 is required for GCMa ubiquitination and for association with the SCF(FBXW2) complex.
The results imply that the interaction specificity between c-Cbl, UbcH7 and UbcH5b is required but not sufficient for transfer of ubiquitin to potential targets.

Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Antigen Profile

Antigen Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Alternative names and synonyms associated with Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2)

ubiquitin conjugating enzyme E2 D2 (UBE2D2) antibody
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) (ube2d2) antibody
ubiquitin-conjugating enzyme E2D 2 (Ube2d2) antibody
ubiquitin conjugating enzyme E2 D2 (Ube2d2) antibody

E2(17)KB2 antibody
E217kB antibody
PUBC1 antibody
Ubc2e antibody
UBC4 antibody
UBC4/5 antibody
UBCH5B antibody
Ube2d2 antibody
zgc:55886 antibody

Protein level used designations for UBE2D2

p53-regulated ubiquitin-conjugating enzyme 1 , ubiquitin carrier protein D2 , ubiquitin-conjugating enzyme E2 D2 , ubiquitin-conjugating enzyme E2-17 kDa 2 , ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5) , ubiquitin-protein ligase D2 , ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) , ubiquitin-conjugating enzyme E2D 2 , E2(17)KB 2 , ubc2e ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme E2(17)KB 2

GENE ID	SPECIES
7322	Homo sapiens
541003	Bos taurus
100194508	Salmo salar
393934	Danio rerio
641452	Rattus norvegicus
446340	Xenopus laevis
416137	Gallus gallus
612742	Canis lupus familiaris
100732779	Cavia porcellus

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Show all anti-Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) Antibodies with Pubmed References

Human Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) interaction partners

Antigen Summary

Alternative names and synonyms associated with Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2)

Protein level used designations for UBE2D2