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anti-Human CAMKK1 Antibodies:
anti-Mouse (Murine) CAMKK1 Antibodies:
anti-Rat (Rattus) CAMKK1 Antibodies:
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Human Polyclonal CAMKK1 Primary Antibody for ICC, IF - ABIN446068
Hamada, Souda, Yoshimura, Sasaguri, Hatanaka, Tasaki, Yoshioka, Ohi, Yamada, Tsutsui, Umekita, Tanimoto: Anti-apoptotic effects of PCP4/PEP19 in human breast cancer cell lines: a novel oncotarget. in Oncotarget 2014
Site-directed mutagenesis analysis revealed that Leu(358) in CaMKKbeta/Ile(322) in CaMKKalpha confer, at least in part, a distinct recognition of AMPK (show PRKAA1 Antibodies) but not of CaMKIalpha (show CAMK1 Antibodies).
CaMKK1 does not play a pivotal role in the calcium signaling cascade regulating adrenal aldosterone production.
CAMKK1 might contribute to the risk of lung cancer in Chinese populations.
CaMKIalpha (show CAMK1 Antibodies) is a widely expressed protein kinase (show CDK7 Antibodies), suggesting that Ca2 (show CA2 Antibodies)+ is likely to be functionally important in the control of mitochondrial dynamics through regulation of Drp1 (show CRMP1 Antibodies) phosphorylation in neurons and other cell types.[CaMKIalpha (show CAMK1 Antibodies)]
Adiponectin activates AMP-activated protein kinase (show PRKAA2 Antibodies) in muscle cells via APPL1 (show APPL1 Antibodies)/LKB1 (show STK11 Antibodies)-dependent and phospholipase C (show PLC Antibodies)/Ca2+/Ca2 (show CA2 Antibodies)+/calmodulin-dependent protein kinase (show CDK7 Antibodies) kinase-dependent pathways
the CaMKK (show CAMKK2 Antibodies)-CaMKIalpha (show CAMK1 Antibodies) cascade is required for the axonal growth effect of Wnt5a (show WNT5A Antibodies) during neuronal polarization.
Data (including data from knockout mice) suggest that up-regulation of Camkk1 and calcium signaling stimulates muscle growth via up-regulation of mTORC1 (mammalian target of rapamycin (show FRAP1 Antibodies) complex 1) signaling and muscle protein biosynthesis.
caCaMKKalpha stimulates glucose uptake additively with insulin (show INS Antibodies), and in insulin (show INS Antibodies)-resistant muscle, and alters the phosphorylation of TBC1D1 (show TBC1D1 Antibodies)/TBC1D4 (show TBC1D4 Antibodies).
ERK (show EPHB2 Antibodies) activation and neurite outgrowth in response to depolarization are mediated by CaMKK (show CAMKK2 Antibodies) activation of CaMKI (show CAMK1 Antibodies)
In muscles from wild-type mice CaMKKalpha increased in vivo deoxyglucose uptake and AMPKalpha1 (show PRKAA1 Antibodies) and -alpha2 activities 2.5-fold.
Data show that CaMKK (show CAMKK2 Antibodies) is the kinase responsible for alpha-lipoic acid induced AMP-activated protein kinase (show PRKAA2 Antibodies) activation in C2C12 myotubes.
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.
, camkk 1
, calcium/calmodulin-dependent protein kinase kinase 1
, calcium/calmodulin-dependent protein kinase kinase 1, alpha
, calcium/calmodulin-dependent protein kinase 1 alpha-like
, calcium/calmodulin-dependent protein kinase kinase 1-like
, CAMKK alpha protein
, caM-KK 1
, caM-KK alpha
, caM-kinase IV kinase
, caM-kinase kinase 1
, caM-kinase kinase alpha
, caMKK 1
, calcium/calmodulin-dependent protein kinase kinase alpha
, caMKK alpha
, calcium calmodulin dependent protein kinase kinase alpha
, alpha CaMKK