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Interferon gamma antibody

Rockland 201-401-c41 IFNG Reactivity: Cow WB, ELISA Host: Rabbit Polyclonal unconjugated
Rockland
Catalog No. ABIN1043777
Supplier Product No.: 201-401-c41
  • Target See all Interferon gamma (IFNG) Antibodies
    Interferon gamma (IFNG)
    Reactivity
    • 217
    • 74
    • 50
    • 27
    • 24
    • 21
    • 17
    • 17
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    Cow
    Host
    • 217
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    • 38
    • 11
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    • 2
    • 2
    • 2
    Rabbit
    Clonality
    • 258
    • 190
    • 1
    Polyclonal
    Conjugate
    • 205
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    • 48
    • 20
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    • 14
    • 7
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Interferon gamma antibody is un-conjugated
    Application
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    Western Blotting (WB), ELISA
    Supplier Product No.
    201-401-c41
    Supplier
    Rockland
    Purpose
    Interferon Gamma Antibody
    Cross-Reactivity (Details)
    This antibody is specific for bovine IFN gamma protein.
    Characteristics
    Synonyms: rabbit anti-IFN gamma, rabbit anti-Interferon gamma, IFNG, BoIFNG
    Purification
    This product was protein A purified from monospecific antiserum by chromatography.
    Immunogen

    Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to the 143 amino acids of the mature Bovine IFN Gamma protein.

    Immunogen Type: Recombinant Protein

    Isotype
    IgG
    Top Product
    Discover our top product IFNG Primary Antibody
  • Application Notes

    Application Note: This protein A purified IFN-gamma antibody has been tested by ELISA and Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 16.9 kDa in size corresponding to bovine IFN gamma by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500-1:2,000

    ELISA Dilution: 1:20,000

    Other: User Optimized

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution

    Reconstitution Volume: 100 μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    Concentration
    1.59 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Expiry Date
    12 months
  • George, Ma, Motyka, Shi, Liu, Griebel: "A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses in vivo." in: Human vaccines & immunotherapeutics, Vol. 16, Issue 4, pp. 779-792, (2020) (PubMed).

    Schroder, Hertzog, Ravasi, Hume: "Interferon-gamma: an overview of signals, mechanisms and functions." in: Journal of leukocyte biology, Vol. 75, Issue 2, pp. 163-89, (2004) (PubMed).

  • Target
    Interferon gamma (IFNG)
    Alternative Name
    IFN gamma (IFNG Products)
    Background
    Background: Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
    Gene ID
    281237
    NCBI Accession
    NP_776511
    UniProt
    A9QXB7
    Pathways
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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