VNN3 antibody (C-Term)
Quick Overview for VNN3 antibody (C-Term) (ABIN1077383)
Target
See all VNN3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- Multiple isoforms of VNN3 are known to exist.
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- VNN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human VNN3.
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Isotype
- IgG
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Application Notes
- VNN3 antibody can be used for detection of VNN3 by Western blot at 0.5 and 1 μg/mL.
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Comment
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(CT) Vascular non-inflammatory molecule 3
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 0.02 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage
- 4 °C/-20 °C
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Storage Comment
- VNN3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
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Expiry Date
- 12 months
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- VNN3 (Vanin 3 (VNN3))
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Alternative Name
- VNN3
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Background
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The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
Synonyms: Vanin 3, Vascular non-inflammatory molecule 3, HSA238982 -
Molecular Weight
- 55 kDa
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Gene ID
- 55350
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UniProt
- Q9NY84
Target
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