CCL2 antibody (C-Term)

Catalog No. ABIN1077434

The Rabbit Monoclonal anti-CCL2 antibody has been validated for WB and ELISA. It is suitable to detect CCL2 in samples from Human, Mouse and Rat.

Quick Overview for CCL2 antibody (C-Term) (ABIN1077434)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CCL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL2 Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal CCL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human CCL2.

Isotype: IgG

Application Details

Application Notes: CCL2 antibody can be used for detection of CCL2 by Western blot at 1 - 2 μg/mL.

Comment:

(CT) Chemokine (C-C motif) ligand 2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: CCL2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: CCL2

Background: CCL2, also known as monocyte chemotactic protein 1 (MCP1), belongs to the intercrine beta (chemokine CC) family. It is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. It is upregulated during infection and inflammation. CCL2 is a potent basophil activator but does not affect eosinophils, whereas the related protein MCP2 stimulates both eosinophils and basophils. MCP3 has been shown to have the broadest range of influence. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.
Synonyms: C-C motif ligand 2, Monocyte chemoattractant protein 1, MCP1, Small-inducible cytokine A2, SCYA2, GDCF-2, SMC-CF, HSMCR30, MCAF

Molecular Weight: 11 kDa (calculated)

Gene ID: 6347

NCBI Accession: NP_002973

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection