FASL antibody (Extracellular Domain)
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- Target See all FASL Antibodies
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This FASL antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Specificity
- GM5F4 recognises FASL transiently expressed on the cell surface of transfected BOSC cells.
- Purification
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding human FasL (extracellular domain)
- Clone
- GM-5F4
- Isotype
- IgG1
- Top Product
- Discover our top product FASL Primary Antibody
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- Application Notes
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Comment
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Synonyms: CD95, Fas ligand
- Restrictions
- For Research Use only
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- Buffer
- PBS, pH 7.2
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C
- Storage Comment
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Alternative Name
- FASL (FASL Products)
- Background
- The FAS ligand (FASL, CD95), a member of the tumor necrosis factor family, induces apoptosis in FAS-bearing cells. GM5F4 against this transmembrane receptor was generated by genetic immunisation.
- UniProt
- P48023
- Pathways
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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