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POU3F2 antibody (AA 214-362)
POU3F2
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
6H12
unconjugated
Product Details anti-POU3F2 Antibody
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Target
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POU3F2
(POU Class 3 Homeobox 2 (POU3F2))
Binding Specificity
All epitopes for POU3F2 antibodies
AA 214-362
Reactivity
All reactivities for POU3F2 antibodies
Human
Host
All hosts for POU3F2 antibodies
Mouse
Clonality
All clonalities for POU3F2 antibodies
Monoclonal
Conjugate
All conjugates for POU3F2 antibodies
This POU3F2 antibody is un-conjugated
Application
All applications for POU3F2 antibodies
Western Blotting (WB), ELISA
Purpose
POU3F2 Antibody
Purification
Purified antibody
Immunogen
Purified recombinant fragment of human POU3F2 (AA: 214-362) expressed in E. Coli.
Clone
6H12
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
ELISA: 1/10000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified antibody in PBS with 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
References for anti-POU3F2 antibody (ABIN1098110)
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Goodall, Carreira, Denat, Kobi, Davidson, Nuciforo, Sturm, Larue, Goding : "Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells. " in: Cancer research , Vol. 68 , Issue 19 , pp. 7788-94 , (2008 ) (PubMed ).
Cobrinik, Francis, Abramson, Lee : "Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells. " in: Molecular cancer , Vol. 5 , pp. 72 , (2007 ) (PubMed ).
Target Details for POU3F2
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Target
POU3F2
(POU Class 3 Homeobox 2 (POU3F2))
Alternative Name
POU3F2 (POU3F2 Products )
Background
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
Molecular Weight
46.9 kDa
Gene ID
5454
UniProt
P20265
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