POU3F2 antibody (AA 214-362)

Catalog No. ABIN1098110

The Mouse Monoclonal anti-POU3F2 antibody has been validated for WB and ELISA. It is suitable to detect POU3F2 in samples from Human. There are 2+ publications available.

Quick Overview for POU3F2 antibody (AA 214-362) (ABIN1098110)

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POU3F2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6H12

Product Details anti-POU3F2 Antibody

Binding Specificity: AA 214-362

Purpose: POU3F2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human POU3F2 (AA: 214-362) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-POU3F2 antibody (ABIN1098110)

Goodall, Carreira, Denat, Kobi, Davidson, Nuciforo, Sturm, Larue, Goding: "Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells." in: Cancer research, Vol. 68, Issue 19, pp. 7788-94, (2008) (PubMed).

Cobrinik, Francis, Abramson, Lee: "Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells." in: Molecular cancer, Vol. 5, pp. 72, (2007) (PubMed).

Target Details for POU3F2

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Alternative Name: POU3F2

Background: This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.

Molecular Weight: 46.9 kDa

Gene ID: 5454

UniProt: P20265