ILK antibody (AA 97-244)

Catalog No. ABIN1098122

The Mouse Monoclonal anti-ILK antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect ILK in samples from Human, Mouse and Monkey. There are 2+ publications available.

Quick Overview for ILK antibody (AA 97-244) (ABIN1098122)

Target: ILK (Integrin-Linked Kinase (ILK))

Reactivity: Human, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This ILK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 3A9

Product Details anti-ILK Antibody

Binding Specificity: AA 97-244

Purpose: ILK Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human ILK (AA: 97-244) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ILK antibody (ABIN1098122)

Taylor, Qiao, Colon, Schlegel, Josifi, Chung: "Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells." in: Surgery, Vol. 150, Issue 2, pp. 162-8, (2011) (PubMed).

Matsui, Assi, Ogawa, Raven, Dedhar, Gleave, Salh, So: "The importance of integrin-linked kinase in the regulation of bladder cancer invasion." in: International journal of cancer. Journal international du cancer, Vol. 130, Issue 3, pp. 521-31, (2011) (PubMed).

Target Details for ILK

Target: ILK (Integrin-Linked Kinase (ILK))

Alternative Name: ILK

Background: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 51.4 kDa

Gene ID: 3611

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration